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Engineering Promiscuous Alcohol Dehydrogenase Activity of a Reductive Aminase AspRedAm for Selective Reduction of Biobased Furans

Catalytic promiscuity is a promising starting point for improving the existing enzymes and even creating novel enzymes. In this work, site-directed mutagenesis was performed to improve promiscuous alcohol dehydrogenase activity of reductive aminase from Aspergillus oryzae (AspRedAm). AspRedAm showed...

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Detalles Bibliográficos
Autores principales:	Jia, Hao-Yu, Yang, Zi-Yue, Chen, Qi, Zong, Min-Hua, Li, Ning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155666/ https://www.ncbi.nlm.nih.gov/pubmed/34055734 http://dx.doi.org/10.3389/fchem.2021.610091

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