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The First Insight Into the Supramolecular System of D,L-α-Difluoromethylornithine: A New Antiviral Perspective

Targeting the polyamine biosynthetic pathway by inhibiting ornithine decarboxylase (ODC) is a powerful approach in the fight against diverse viruses, including SARS-CoV-2. Difluoromethylornithine (DFMO, eflornithine) is the best-known inhibitor of ODC and a broad-spectrum, unique therapeutical agent...

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Detalles Bibliográficos
Autores principales:	Bojarska, Joanna, New, Roger, Borowiecki, Paweł, Remko, Milan, Breza, Martin, Madura, Izabela D., Fruziński, Andrzej, Pietrzak, Anna, Wolf, Wojciech M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155678/ https://www.ncbi.nlm.nih.gov/pubmed/34055746 http://dx.doi.org/10.3389/fchem.2021.679776

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