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Investigating the Potential of Transdermal Delivery of Avanafil Using Vitamin E-TPGS Based Mixed Micelles Loaded Films

To avoid the first-pass metabolism of avanafil (AVA) and its altered absorption in the presence of food after oral administration, this study aimed to investigate the potential of TPGS-based mixed micelle (MM)-loaded film for transdermal delivery and the enhancement of bioavailability. A Box–Behnken...

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Detalles Bibliográficos
Autores principales: Alamoudi, Abdullah A., Ahmed, Osama A. A., El-Say, Khalid M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155967/
https://www.ncbi.nlm.nih.gov/pubmed/34067893
http://dx.doi.org/10.3390/pharmaceutics13050739