An Overview of the Chemical Characteristics, Bioactivity and Achievements Regarding the Therapeutic Usage of Acetogenins from Annona cherimola Mill.

Annona cherimola Mill., or the custard apple, is one of the species belonging to the Annonaceae family, is widely used in traditional medicine, and has been reported to be a valuable source of bioactive compounds. A unique class of secondary metabolites derived from this family are Annonaceous aceto...

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Autores principales: Durán, Alexandra G., Gutiérrez, M. Teresa, Mejías, Francisco J. R., Molinillo, José M. G., Macías, Francisco A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155978/
https://www.ncbi.nlm.nih.gov/pubmed/34069113
http://dx.doi.org/10.3390/molecules26102926
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author Durán, Alexandra G.
Gutiérrez, M. Teresa
Mejías, Francisco J. R.
Molinillo, José M. G.
Macías, Francisco A.
author_facet Durán, Alexandra G.
Gutiérrez, M. Teresa
Mejías, Francisco J. R.
Molinillo, José M. G.
Macías, Francisco A.
author_sort Durán, Alexandra G.
collection PubMed
description Annona cherimola Mill., or the custard apple, is one of the species belonging to the Annonaceae family, is widely used in traditional medicine, and has been reported to be a valuable source of bioactive compounds. A unique class of secondary metabolites derived from this family are Annonaceous acetogenins, lipophilic polyketides considered to be amongst the most potent antitumor compounds. This review provides an overview of the chemical diversity, isolation procedures, bioactivity, modes of application and synthetic derivatives of acetogenins from A. cherimola Mill.
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spelling pubmed-81559782021-05-28 An Overview of the Chemical Characteristics, Bioactivity and Achievements Regarding the Therapeutic Usage of Acetogenins from Annona cherimola Mill. Durán, Alexandra G. Gutiérrez, M. Teresa Mejías, Francisco J. R. Molinillo, José M. G. Macías, Francisco A. Molecules Review Annona cherimola Mill., or the custard apple, is one of the species belonging to the Annonaceae family, is widely used in traditional medicine, and has been reported to be a valuable source of bioactive compounds. A unique class of secondary metabolites derived from this family are Annonaceous acetogenins, lipophilic polyketides considered to be amongst the most potent antitumor compounds. This review provides an overview of the chemical diversity, isolation procedures, bioactivity, modes of application and synthetic derivatives of acetogenins from A. cherimola Mill. MDPI 2021-05-14 /pmc/articles/PMC8155978/ /pubmed/34069113 http://dx.doi.org/10.3390/molecules26102926 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Durán, Alexandra G.
Gutiérrez, M. Teresa
Mejías, Francisco J. R.
Molinillo, José M. G.
Macías, Francisco A.
An Overview of the Chemical Characteristics, Bioactivity and Achievements Regarding the Therapeutic Usage of Acetogenins from Annona cherimola Mill.
title An Overview of the Chemical Characteristics, Bioactivity and Achievements Regarding the Therapeutic Usage of Acetogenins from Annona cherimola Mill.
title_full An Overview of the Chemical Characteristics, Bioactivity and Achievements Regarding the Therapeutic Usage of Acetogenins from Annona cherimola Mill.
title_fullStr An Overview of the Chemical Characteristics, Bioactivity and Achievements Regarding the Therapeutic Usage of Acetogenins from Annona cherimola Mill.
title_full_unstemmed An Overview of the Chemical Characteristics, Bioactivity and Achievements Regarding the Therapeutic Usage of Acetogenins from Annona cherimola Mill.
title_short An Overview of the Chemical Characteristics, Bioactivity and Achievements Regarding the Therapeutic Usage of Acetogenins from Annona cherimola Mill.
title_sort overview of the chemical characteristics, bioactivity and achievements regarding the therapeutic usage of acetogenins from annona cherimola mill.
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155978/
https://www.ncbi.nlm.nih.gov/pubmed/34069113
http://dx.doi.org/10.3390/molecules26102926
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