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From Antisense RNA to RNA Modification: Therapeutic Potential of RNA-Based Technologies
Therapeutic oligonucleotides interact with a target RNA via Watson-Crick complementarity, affecting RNA-processing reactions such as mRNA degradation, pre-mRNA splicing, or mRNA translation. Since they were proposed decades ago, several have been approved for clinical use to correct genetic mutation...
Autores principales: | Adachi, Hironori, Hengesbach, Martin, Yu, Yi-Tao, Morais, Pedro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156014/ https://www.ncbi.nlm.nih.gov/pubmed/34068948 http://dx.doi.org/10.3390/biomedicines9050550 |
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