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Metronomic 5-Fluorouracil Delivery Primes Skeletal Muscle for Myopathy but Does Not Cause Cachexia

Skeletal myopathy encompasses both atrophy and dysfunction and is a prominent event in cancer and chemotherapy-induced cachexia. Here, we investigate the effects of a chemotherapeutic agent, 5-fluorouracil (5FU), on skeletal muscle mass and function, and whether small-molecule therapeutic candidate,...

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Detalles Bibliográficos
Autores principales:	Campelj, Dean G., Timpani, Cara A., Cree, Tabitha, Petersen, Aaron C., Hayes, Alan, Goodman, Craig A., Rybalka, Emma
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156038/ https://www.ncbi.nlm.nih.gov/pubmed/34067869 http://dx.doi.org/10.3390/ph14050478

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