Therapeutic Silencing of BCL-2 Using NK Cell-Derived Exosomes as a Novel Therapeutic Approach in Breast Cancer

SIMPLE SUMMARY: Overexpression of the antiapoptotic protein BCL-2 is correlated with estrogen receptor (ER) expression in breast cancer and plays an important role for disease pathophysiology. Here, we conceptualized a novel treatment strategy by targeting ER(+) breast cancer with NK cell-derived ex...

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Autores principales: Kaban, Kübra, Hinterleitner, Clemens, Zhou, Yanjun, Salva, Emine, Kantarci, Ayse Gülten, Salih, Helmut R., Märklin, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156181/
https://www.ncbi.nlm.nih.gov/pubmed/34063475
http://dx.doi.org/10.3390/cancers13102397

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