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Sambucus Nigra Extracts–Natural Antioxidants and Antimicrobial Compounds

Due to the health-promoting properties of elderberry fruits, which result from their rich chemical composition, this raw material is widely used in herbal medicine and the food industry. The aim of the study was to demonstrate the antibacterial activity of the elderberry fruit extracts. The research...

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Autores principales: Przybylska-Balcerek, Anna, Szablewski, Tomasz, Szwajkowska-Michałek, Lidia, Świerk, Dariusz, Cegielska-Radziejewska, Renata, Krejpcio, Zbigniew, Suchowilska, Elżbieta, Tomczyk, Łukasz, Stuper-Szablewska, Kinga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156197/
https://www.ncbi.nlm.nih.gov/pubmed/34068909
http://dx.doi.org/10.3390/molecules26102910
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author Przybylska-Balcerek, Anna
Szablewski, Tomasz
Szwajkowska-Michałek, Lidia
Świerk, Dariusz
Cegielska-Radziejewska, Renata
Krejpcio, Zbigniew
Suchowilska, Elżbieta
Tomczyk, Łukasz
Stuper-Szablewska, Kinga
author_facet Przybylska-Balcerek, Anna
Szablewski, Tomasz
Szwajkowska-Michałek, Lidia
Świerk, Dariusz
Cegielska-Radziejewska, Renata
Krejpcio, Zbigniew
Suchowilska, Elżbieta
Tomczyk, Łukasz
Stuper-Szablewska, Kinga
author_sort Przybylska-Balcerek, Anna
collection PubMed
description Due to the health-promoting properties of elderberry fruits, which result from their rich chemical composition, this raw material is widely used in herbal medicine and the food industry. The aim of the study was to demonstrate the antibacterial activity of the elderberry fruit extracts. The research showed that the content of phenolic acids and flavonoids in the extracts determined their antibacterial activity. The research showed that the content of phenolic acids and flavonoids in the extracts determined their antibacterial activity. The following phenolic acids were predominant: chlorogenic acid, sinapic acid, and t-cinnamic acid. Their average content was, respectively, 139.09, 72.84, 51.29 mg/g extract. Rutin and quercetin (their average content was 1105.39 and 306.6 mg/g extract, respectively) were the dominant flavonoids. The research showed that the elderberry polyphenol extracts exhibited activity against selected strains of bacteria within the concentration range of 0.5–0.05%. The following bacteria were the most sensitive to the extracts: Micrococcus luteus, Proteus mirabilis, Pseudomonas fragii, and Escherichia coli. Of the compounds under analysis, apigenin, kaempferol and ferulic, protocatechuic, and p-coumarin acids had the greatest influence on the high antibacterial activity of elderberry extracts. The results of the microbiological and chemical analyses of the composition of the extracts were analyzed statistically to indicate the bioactive compounds of the greatest antimicrobial significance.
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spelling pubmed-81561972021-05-28 Sambucus Nigra Extracts–Natural Antioxidants and Antimicrobial Compounds Przybylska-Balcerek, Anna Szablewski, Tomasz Szwajkowska-Michałek, Lidia Świerk, Dariusz Cegielska-Radziejewska, Renata Krejpcio, Zbigniew Suchowilska, Elżbieta Tomczyk, Łukasz Stuper-Szablewska, Kinga Molecules Article Due to the health-promoting properties of elderberry fruits, which result from their rich chemical composition, this raw material is widely used in herbal medicine and the food industry. The aim of the study was to demonstrate the antibacterial activity of the elderberry fruit extracts. The research showed that the content of phenolic acids and flavonoids in the extracts determined their antibacterial activity. The research showed that the content of phenolic acids and flavonoids in the extracts determined their antibacterial activity. The following phenolic acids were predominant: chlorogenic acid, sinapic acid, and t-cinnamic acid. Their average content was, respectively, 139.09, 72.84, 51.29 mg/g extract. Rutin and quercetin (their average content was 1105.39 and 306.6 mg/g extract, respectively) were the dominant flavonoids. The research showed that the elderberry polyphenol extracts exhibited activity against selected strains of bacteria within the concentration range of 0.5–0.05%. The following bacteria were the most sensitive to the extracts: Micrococcus luteus, Proteus mirabilis, Pseudomonas fragii, and Escherichia coli. Of the compounds under analysis, apigenin, kaempferol and ferulic, protocatechuic, and p-coumarin acids had the greatest influence on the high antibacterial activity of elderberry extracts. The results of the microbiological and chemical analyses of the composition of the extracts were analyzed statistically to indicate the bioactive compounds of the greatest antimicrobial significance. MDPI 2021-05-14 /pmc/articles/PMC8156197/ /pubmed/34068909 http://dx.doi.org/10.3390/molecules26102910 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Przybylska-Balcerek, Anna
Szablewski, Tomasz
Szwajkowska-Michałek, Lidia
Świerk, Dariusz
Cegielska-Radziejewska, Renata
Krejpcio, Zbigniew
Suchowilska, Elżbieta
Tomczyk, Łukasz
Stuper-Szablewska, Kinga
Sambucus Nigra Extracts–Natural Antioxidants and Antimicrobial Compounds
title Sambucus Nigra Extracts–Natural Antioxidants and Antimicrobial Compounds
title_full Sambucus Nigra Extracts–Natural Antioxidants and Antimicrobial Compounds
title_fullStr Sambucus Nigra Extracts–Natural Antioxidants and Antimicrobial Compounds
title_full_unstemmed Sambucus Nigra Extracts–Natural Antioxidants and Antimicrobial Compounds
title_short Sambucus Nigra Extracts–Natural Antioxidants and Antimicrobial Compounds
title_sort sambucus nigra extracts–natural antioxidants and antimicrobial compounds
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156197/
https://www.ncbi.nlm.nih.gov/pubmed/34068909
http://dx.doi.org/10.3390/molecules26102910
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