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Descriptors of Cytochrome Inhibitors and Useful Machine Learning Based Methods for the Design of Safer Drugs

Roughly 2.8% of annual hospitalizations are a result of adverse drug interactions in the United States, representing more than 245,000 hospitalizations. Drug–drug interactions commonly arise from major cytochrome P450 (CYP) inhibition. Various approaches are routinely employed in order to reduce the...

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Detalles Bibliográficos
Autores principales: Beck, Tyler C., Beck, Kyle R., Morningstar, Jordan, Benjamin, Menny M., Norris, Russell A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156202/
https://www.ncbi.nlm.nih.gov/pubmed/34067565
http://dx.doi.org/10.3390/ph14050472