Asymmetric Synthesis of Tetrahydroisoquinoline Derivatives through 1,3-Dipolar Cycloaddition of C,N-Cyclic Azomethine Imines with Allyl Alkyl Ketones

A [3 + 2] 1,3-Dipolar cycloaddition of C,N-cyclic azomethine imines with allyl alkyl ketones has been achieved. The reaction proceeds under mild conditions and tolerates a wide range of functional groups. An array of tetrahydroisoquinoline derivatives is generally constructed with good diastereosele...

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Detalles Bibliográficos
Autores principales: Feng, Guipeng, Ma, Guoyang, Chen, Wenyan, Xu, Shaohong, Wang, Kaikai, Wang, Shaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156229/
https://www.ncbi.nlm.nih.gov/pubmed/34067645
http://dx.doi.org/10.3390/molecules26102969

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