Transferrin Modified GSH Sensitive Hyaluronic Acid Derivative Micelle to Deliver HSP90 Inhibitors to Enhance the Therapeutic Efficacy of Brain Cancers

SIMPLE SUMMARY: Heat shock protein 90 (HSP90) is a key element of a multi-chaperone complex involved in the stabilizing of many client proteins, oncoproteins, which play essential roles in tumorigenesis. As the result, HSP90 has been taken as a promising target for anticancer therapies. AUY922 has g...

Descripción completa

Detalles Bibliográficos
Autores principales: Debele, Tilahun Ayane, Wu, Ping-Ching, Wei, Yu-Feng, Chuang, Jian-Ying, Chang, Kwang-Yu, Tsai, Jui-Hung, Su, Wen-Pin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156315/
https://www.ncbi.nlm.nih.gov/pubmed/34069106
http://dx.doi.org/10.3390/cancers13102375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156315/
https://www.ncbi.nlm.nih.gov/pubmed/34069106
http://dx.doi.org/10.3390/cancers13102375

Ejemplares similares