Clinical Implications of Exosomes: Targeted Drug Delivery for Cancer Treatment

Exosomes are nanoscale vesicles generated by cells for intercellular communication. Due to their composition, significant research has been conducted to transform these particles into specific delivery systems for various disease states. In this review, we discuss the common isolation and loading me...

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Detalles Bibliográficos
Autores principales: Massey, Andrew E., Malik, Shabnam, Sikander, Mohammad, Doxtater, Kyle A., Tripathi, Manish K., Khan, Sheema, Yallapu, Murali M., Jaggi, Meena, Chauhan, Subhash C., Hafeez, Bilal B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156384/
https://www.ncbi.nlm.nih.gov/pubmed/34067896
http://dx.doi.org/10.3390/ijms22105278
Descripción
Sumario:Exosomes are nanoscale vesicles generated by cells for intercellular communication. Due to their composition, significant research has been conducted to transform these particles into specific delivery systems for various disease states. In this review, we discuss the common isolation and loading methods of exosomes, some of the major roles of exosomes in the tumor microenvironment, as well as discuss recent applications of exosomes as drug delivery vessels and the resulting clinical implications.

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