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Inhibition of the PI3K/mTOR Pathway in Breast Cancer to Enhance Response to Immune Checkpoint Inhibitors in Breast Cancer

Objectives: Inhibition of the PI3K/mTOR pathway suppresses breast cancer (BC) growth, enhances anti-tumor immune responses, and works synergistically with immune checkpoint inhibitors (ICI). The objective here was to identify a subclass of PI3K inhibitors that, when combined with paclitaxel, is effe...

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Detalles Bibliográficos
Autores principales: Yan, Chi, Yang, Jinming, Saleh, Nabil, Chen, Sheau-Chiann, Ayers, Gregory D., Abramson, Vandana G., Mayer, Ingrid A., Richmond, Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156389/
https://www.ncbi.nlm.nih.gov/pubmed/34069042
http://dx.doi.org/10.3390/ijms22105207