Orai1 Channel Regulates Human-Activated Pancreatic Stellate Cell Proliferation and TGF(β1) Secretion through the AKT Signaling Pathway

SIMPLE SUMMARY: Activated pancreatic stellate cells (aPSCs), the main source of cancer-associated fibroblasts in pancreatic ductal adenocarcinoma (PDAC), are well known as the key actor of the abundant fibrotic stroma development surrounding the tumor cells. In permanent communication with the tumor...

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Detalles Bibliográficos
Autores principales: Radoslavova, Silviya, Folcher, Antoine, Lefebvre, Thibaut, Kondratska, Kateryna, Guénin, Stéphanie, Dhennin-Duthille, Isabelle, Gautier, Mathieu, Prevarskaya, Natalia, Ouadid-Ahidouch, Halima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156432/
https://www.ncbi.nlm.nih.gov/pubmed/34063470
http://dx.doi.org/10.3390/cancers13102395

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