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Recent Progress in Antimicrobial Strategies for Resin-Based Restoratives
Repairing tooth defects with dental resin composites is currently the most commonly used method due to their tooth-colored esthetics and photocuring properties. However, the higher than desirable failure rate and moderate service life are the biggest challenges the composites currently face. Seconda...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156482/ https://www.ncbi.nlm.nih.gov/pubmed/34069312 http://dx.doi.org/10.3390/polym13101590 |
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author | Sun, Qiannan Zhang, Lingyun Bai, Rushui Zhuang, Zimeng Zhang, Yunfan Yu, Tingting Peng, Liying Xin, Tianyi Chen, Si Han, Bing |
author_facet | Sun, Qiannan Zhang, Lingyun Bai, Rushui Zhuang, Zimeng Zhang, Yunfan Yu, Tingting Peng, Liying Xin, Tianyi Chen, Si Han, Bing |
author_sort | Sun, Qiannan |
collection | PubMed |
description | Repairing tooth defects with dental resin composites is currently the most commonly used method due to their tooth-colored esthetics and photocuring properties. However, the higher than desirable failure rate and moderate service life are the biggest challenges the composites currently face. Secondary caries is one of the most common reasons leading to repair failure. Therefore, many attempts have been carried out on the development of a new generation of antimicrobial and therapeutic dental polymer composite materials to inhibit dental caries and prolong the lifespan of restorations. These new antimicrobial materials can inhibit the formation of biofilms, reduce acid production from bacteria and the occurrence of secondary caries. These results are encouraging and open the doors to future clinical studies on the therapeutic value of antimicrobial dental resin-based restoratives. However, antimicrobial resins still face challenges such as biocompatibility, drug resistance and uncontrolled release of antimicrobial agents. In the future, we should focus on the development of more efficient, durable and smart antimicrobial dental resins. This article focuses on the most recent 5 years of research, reviews the current antimicrobial strategies of composite resins, and introduces representative antimicrobial agents and their antimicrobial mechanisms. |
format | Online Article Text |
id | pubmed-8156482 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-81564822021-05-28 Recent Progress in Antimicrobial Strategies for Resin-Based Restoratives Sun, Qiannan Zhang, Lingyun Bai, Rushui Zhuang, Zimeng Zhang, Yunfan Yu, Tingting Peng, Liying Xin, Tianyi Chen, Si Han, Bing Polymers (Basel) Review Repairing tooth defects with dental resin composites is currently the most commonly used method due to their tooth-colored esthetics and photocuring properties. However, the higher than desirable failure rate and moderate service life are the biggest challenges the composites currently face. Secondary caries is one of the most common reasons leading to repair failure. Therefore, many attempts have been carried out on the development of a new generation of antimicrobial and therapeutic dental polymer composite materials to inhibit dental caries and prolong the lifespan of restorations. These new antimicrobial materials can inhibit the formation of biofilms, reduce acid production from bacteria and the occurrence of secondary caries. These results are encouraging and open the doors to future clinical studies on the therapeutic value of antimicrobial dental resin-based restoratives. However, antimicrobial resins still face challenges such as biocompatibility, drug resistance and uncontrolled release of antimicrobial agents. In the future, we should focus on the development of more efficient, durable and smart antimicrobial dental resins. This article focuses on the most recent 5 years of research, reviews the current antimicrobial strategies of composite resins, and introduces representative antimicrobial agents and their antimicrobial mechanisms. MDPI 2021-05-14 /pmc/articles/PMC8156482/ /pubmed/34069312 http://dx.doi.org/10.3390/polym13101590 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Sun, Qiannan Zhang, Lingyun Bai, Rushui Zhuang, Zimeng Zhang, Yunfan Yu, Tingting Peng, Liying Xin, Tianyi Chen, Si Han, Bing Recent Progress in Antimicrobial Strategies for Resin-Based Restoratives |
title | Recent Progress in Antimicrobial Strategies for Resin-Based Restoratives |
title_full | Recent Progress in Antimicrobial Strategies for Resin-Based Restoratives |
title_fullStr | Recent Progress in Antimicrobial Strategies for Resin-Based Restoratives |
title_full_unstemmed | Recent Progress in Antimicrobial Strategies for Resin-Based Restoratives |
title_short | Recent Progress in Antimicrobial Strategies for Resin-Based Restoratives |
title_sort | recent progress in antimicrobial strategies for resin-based restoratives |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156482/ https://www.ncbi.nlm.nih.gov/pubmed/34069312 http://dx.doi.org/10.3390/polym13101590 |
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