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Stability across the Whole Nuclear Genome in the Presence and Absence of DNA Mismatch Repair

We describe the contribution of DNA mismatch repair (MMR) to the stability of the eukaryotic nuclear genome as determined by whole-genome sequencing. To date, wild-type nuclear genome mutation rates are known for over 40 eukaryotic species, while measurements in mismatch repair-defective organisms a...

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Detalles Bibliográficos
Autores principales: Lujan, Scott Alexander, Kunkel, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156620/
https://www.ncbi.nlm.nih.gov/pubmed/34067668
http://dx.doi.org/10.3390/cells10051224