Cargando…

The TRPA1 Agonist Cinnamaldehyde Induces the Secretion of HCO(3)(−) by the Porcine Colon

A therapeutic potential of the TRPA1 channel agonist cinnamaldehyde for use in inflammatory bowel disease is emerging, but the mechanisms are unclear. Semi-quantitative qPCR of various parts of the porcine gastrointestinal tract showed that mRNA for TRPA1 was highest in the colonic mucosa. In Ussing...

Descripción completa

Detalles Bibliográficos
Autores principales:	Manneck, David, Manz, Gisela, Braun, Hannah-Sophie, Rosendahl, Julia, Stumpff, Friederike
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156935/ https://www.ncbi.nlm.nih.gov/pubmed/34068986 http://dx.doi.org/10.3390/ijms22105198

Ejemplares similares

News in caecal signalling: the role of propionate in microbial-epithelial crosstalk
por: Stumpff, Friederike, et al.
Publicado: (2021)

TRPA1 Agonist Cinnamaldehyde Decreases Adipogenesis in 3T3-L1 Cells More Potently than the Non-agonist Structural Analog Cinnamyl Isobutyrate
por: Hoi, Julia K., et al.
Publicado: (2020)

Involvement of TRPA1 in the cinnamaldehyde-induced pulpal blood flow change in the feline dental pulp
por: Kim, Dokyung, et al.
Publicado: (2016)

Cinnamaldehyde elicits itch behavior via TRPV1 and TRPV4 but not TRPA1
por: Domocos, Dan, et al.
Publicado: (2020)

Structure-Dependent Effects of Cinnamaldehyde Derivatives on TRPA1-Induced Serotonin Release in Human Intestinal Cell Models
por: Lieder, Barbara, et al.
Publicado: (2020)

Correction to Structure-Dependent Effects of Cinnamaldehyde Derivatives on TRPA1-Induced Serotonin Release in Human Intestinal Cell Models
por: Lieder, Barbara, et al.
Publicado: (2020)

Aerobic exercises regulate the epididymal anion homeostasis of high-fat diet-induced obese rats through TRPA1-mediated Cl(−) and HCO(3)(−) secretion
por: Gao, Dong-Dong, et al.
Publicado: (2023)

Cinnamaldehyde and cinnamaldehyde-containing micelles induce relaxation of isolated porcine coronary arteries: role of nitric oxide and calcium
por: Raffai, Gábor, et al.
Publicado: (2014)

Intracolonic Administration of the TRPA1 Agonist Allyl Isothiocyanate Stimulates Colonic Motility and Defecation in Conscious Dogs
por: Someya, Soutoku, et al.
Publicado: (2015)

Regulating effect of TongXie-YaoFang on colonic epithelial secretion via Cl(-) and HCO(3)(-) channel
por: Yang, Cheng, et al.
Publicado: (2016)

The Agonist Action of Alkylphenols on TRPA1 Relates to Their Effects on Membrane Lipid Order: Implications for TRPA1-Mediated Chemosensation
por: Startek, Justyna B., et al.
Publicado: (2021)

The role of HCO(3)(–) in propionate-induced anion secretion across rat caecal epithelium
por: Ballout, Jasmin, et al.
Publicado: (2021)

Identification of Functionally Distinct Na-HCO(3) Co-Transporters in Colon
por: Barmeyer, Christian, et al.
Publicado: (2013)

Ca(2+) signaling in HCO(3)(−) secretion and protection of upper GI tract
por: He, Jialin, et al.
Publicado: (2017)

The TRPA1 Agonist, Methyl Syringate Suppresses Food Intake and Gastric Emptying
por: Kim, Min Jung, et al.
Publicado: (2013)

Effects of N-glycosylation of the human cation channel TRPA1 on agonist-sensitivity
por: Egan, Timothy J., et al.
Publicado: (2016)

Identification of Natural Compound Carnosol as a Novel TRPA1 Receptor Agonist
por: Zhai, Chenxi, et al.
Publicado: (2014)

Five hTRPA1 Agonists Found in Indigenous Korean Mint, Agastache rugosa
por: Moon, Hana, et al.
Publicado: (2015)

New natural agonists of the transient receptor potential Ankyrin 1 (TRPA1) channel
por: Legrand, Coline, et al.
Publicado: (2020)

The Effect of Cinnamaldehyde on iNOS Activity and NO-Induced Islet Insulin Secretion in High-Fat-Diet Rats
por: Ataie, Zomorrod, et al.
Publicado: (2021)

Distension evoked mucosal secretion in human and porcine colon in vitro
por: Elfers, Kristin, et al.
Publicado: (2023)

Dietary supplementation of essential oils in dairy cows: evidence for stimulatory effects on nutrient absorption
por: Braun, H.-S., et al.
Publicado: (2018)

TRPA1 Channel Activation Inhibits Motor Activity in the Mouse Colon
por: Hassan, Abdul-Azim, et al.
Publicado: (2020)

Structural Moieties Required for Cinnamaldehyde-Related Compounds to Inhibit Canonical IL-1β Secretion
por: Ho, Su-Chen, et al.
Publicado: (2018)

Coronavirus humains (HCoV)
por: Vabret, A., et al.
Publicado: (2009)

Prerequisite Binding Modes Determine the Dynamics of Action of Covalent Agonists of Ion Channel TRPA1
por: Zsidó, Balázs Zoltán, et al.
Publicado: (2021)

HCO(3)(−) Secretion by Murine Nasal Submucosal Gland Serous Acinar Cells during Ca(2+)-stimulated Fluid Secretion
por: Lee, Robert J., et al.
Publicado: (2008)

Adaptation of the endemic coronaviruses HCoV-OC43 and HCoV-229E to the human host
por: Forni, Diego, et al.
Publicado: (2021)

Cellular remodeling of HCO3(-)-secreting cells in rabbit renal collecting duct in response to an acidic environment
Publicado: (1989)

Impaired PGE(2)-stimulated Cl(-) and HCO(3)(-) secretion contributes to cystic fibrosis airway disease
por: Sellers, Zachary M., et al.
Publicado: (2017)

(E)-2-Hydroxycinnamaldehyde
por: Kang, Ki-Tae, et al.
Publicado: (2013)

Characteristics and hazards of the cinnamaldehyde oxidation process
por: Yu, Chang, et al.
Publicado: (2020)

In vivo and in vitro mutagenicity of perillaldehyde and cinnamaldehyde
por: Honma, Masamitsu, et al.
Publicado: (2021)

Cinnamaldehyde-Contained Polymers and Their Biomedical Applications
por: Zhang, Guangyan, et al.
Publicado: (2023)

Cinnamaldehyde–cucurbituril complex: investigation of loading efficiency and its role in enhancing cinnamaldehyde in vitro anti-tumor activity
por: Al Tbakhi, Bayan, et al.
Publicado: (2022)

Stress Conditions Induced by Carvacrol and Cinnamaldehyde on Acinetobacter baumannii
por: Montagu, Angélique, et al.
Publicado: (2016)

The Effect of Anti-Chemokine Oral Drug XC8 on Cough Triggered by The Agonists of TRPA1 But Not TRPV1 Channels in Guinea Pigs
por: Romanova, Julia, et al.
Publicado: (2022)

Extracellular Hco(3) (−) Dependence of Electrogenic Na/Hco(3) Cotransporters Cloned from Salamander and Rat Kidney
por: Grichtchenko, Irina I., et al.
Publicado: (2000)

Titration of Human Coronaviruses, HCoV-229E and HCoV-OC43, by an Indirect Immunoperoxidase Assay
por: Lambert, Francine, et al.
Publicado: (2007)

Trans-Cinnamaldehyde, Carvacrol, and Eugenol Reduce Campylobacter jejuni Colonization Factors and Expression of Virulence Genes in Vitro
por: Upadhyay, Abhinav, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_3glh80ukk4ehr6umqlm70f2fpb