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Distinct Concentration-Dependent Molecular Pathways Regulate Bone Cell Responses to Cobalt and Chromium Exposure from Joint Replacement Prostheses

Systemic cobalt (Co) and chromium (Cr) concentrations may be elevated in patients with metal joint replacement prostheses. Several studies have highlighted the detrimental effects of this exposure on bone cells in vitro, but the underlying mechanisms remain unclear. In this study, we use whole-genom...

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Detalles Bibliográficos
Autores principales:	Shah, Karan M., Dunning, Mark J., Gartland, Alison, Wilkinson, J. Mark
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156984/ https://www.ncbi.nlm.nih.gov/pubmed/34069294 http://dx.doi.org/10.3390/ijms22105225

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