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Evolution of Reproductive Life History in Mammals and the Associated Change of Functional Constraints
Phylogenetic trees based on multiple genomic loci enable us to estimate the evolution of functional constraints that operate on genes based on lineage-specific fluctuation of the evolutionary rate at particular gene loci, “gene–branch interactions”. Using this information as predictors, our previous...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157036/ https://www.ncbi.nlm.nih.gov/pubmed/34068942 http://dx.doi.org/10.3390/genes12050740 |
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author | Wu, Jiaqi Yonezawa, Takahiro Kishino, Hirohisa |
author_facet | Wu, Jiaqi Yonezawa, Takahiro Kishino, Hirohisa |
author_sort | Wu, Jiaqi |
collection | PubMed |
description | Phylogenetic trees based on multiple genomic loci enable us to estimate the evolution of functional constraints that operate on genes based on lineage-specific fluctuation of the evolutionary rate at particular gene loci, “gene–branch interactions”. Using this information as predictors, our previous work inferred that the common ancestor of placental mammals was nocturnal, insectivorous, solitary, and bred seasonally. Here, we added seven new continuous traits including lifespan, bodyweight, and five reproduction-related traits and inferred the coevolution network of 14 core life history traits for 89 mammals. In this network, bodyweight and lifespan are not directly connected to each other; instead, their correlation is due to both of them coevolving with gestation period. Diurnal mammals are more likely to be monogamous than nocturnal mammals, while arboreal mammals tend to have a smaller litter size than terrestrial mammals. Coevolution between diet and the seasonal breeding behavior test shows that year-round breeding preceded the dietary change to omnivory, while seasonal breeding preceded the dietary change to carnivory. We also discuss the evolution of reproductive strategy of mammals. Genes selected as predictors were identified as well; for example, genes function as tumor suppressor were selected as predictors of weaning age. |
format | Online Article Text |
id | pubmed-8157036 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-81570362021-05-28 Evolution of Reproductive Life History in Mammals and the Associated Change of Functional Constraints Wu, Jiaqi Yonezawa, Takahiro Kishino, Hirohisa Genes (Basel) Article Phylogenetic trees based on multiple genomic loci enable us to estimate the evolution of functional constraints that operate on genes based on lineage-specific fluctuation of the evolutionary rate at particular gene loci, “gene–branch interactions”. Using this information as predictors, our previous work inferred that the common ancestor of placental mammals was nocturnal, insectivorous, solitary, and bred seasonally. Here, we added seven new continuous traits including lifespan, bodyweight, and five reproduction-related traits and inferred the coevolution network of 14 core life history traits for 89 mammals. In this network, bodyweight and lifespan are not directly connected to each other; instead, their correlation is due to both of them coevolving with gestation period. Diurnal mammals are more likely to be monogamous than nocturnal mammals, while arboreal mammals tend to have a smaller litter size than terrestrial mammals. Coevolution between diet and the seasonal breeding behavior test shows that year-round breeding preceded the dietary change to omnivory, while seasonal breeding preceded the dietary change to carnivory. We also discuss the evolution of reproductive strategy of mammals. Genes selected as predictors were identified as well; for example, genes function as tumor suppressor were selected as predictors of weaning age. MDPI 2021-05-14 /pmc/articles/PMC8157036/ /pubmed/34068942 http://dx.doi.org/10.3390/genes12050740 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Wu, Jiaqi Yonezawa, Takahiro Kishino, Hirohisa Evolution of Reproductive Life History in Mammals and the Associated Change of Functional Constraints |
title | Evolution of Reproductive Life History in Mammals and the Associated Change of Functional Constraints |
title_full | Evolution of Reproductive Life History in Mammals and the Associated Change of Functional Constraints |
title_fullStr | Evolution of Reproductive Life History in Mammals and the Associated Change of Functional Constraints |
title_full_unstemmed | Evolution of Reproductive Life History in Mammals and the Associated Change of Functional Constraints |
title_short | Evolution of Reproductive Life History in Mammals and the Associated Change of Functional Constraints |
title_sort | evolution of reproductive life history in mammals and the associated change of functional constraints |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157036/ https://www.ncbi.nlm.nih.gov/pubmed/34068942 http://dx.doi.org/10.3390/genes12050740 |
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