Cargando…

Evolution of Reproductive Life History in Mammals and the Associated Change of Functional Constraints

Phylogenetic trees based on multiple genomic loci enable us to estimate the evolution of functional constraints that operate on genes based on lineage-specific fluctuation of the evolutionary rate at particular gene loci, “gene–branch interactions”. Using this information as predictors, our previous...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Jiaqi, Yonezawa, Takahiro, Kishino, Hirohisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157036/
https://www.ncbi.nlm.nih.gov/pubmed/34068942
http://dx.doi.org/10.3390/genes12050740
_version_ 1783699589358944256
author Wu, Jiaqi
Yonezawa, Takahiro
Kishino, Hirohisa
author_facet Wu, Jiaqi
Yonezawa, Takahiro
Kishino, Hirohisa
author_sort Wu, Jiaqi
collection PubMed
description Phylogenetic trees based on multiple genomic loci enable us to estimate the evolution of functional constraints that operate on genes based on lineage-specific fluctuation of the evolutionary rate at particular gene loci, “gene–branch interactions”. Using this information as predictors, our previous work inferred that the common ancestor of placental mammals was nocturnal, insectivorous, solitary, and bred seasonally. Here, we added seven new continuous traits including lifespan, bodyweight, and five reproduction-related traits and inferred the coevolution network of 14 core life history traits for 89 mammals. In this network, bodyweight and lifespan are not directly connected to each other; instead, their correlation is due to both of them coevolving with gestation period. Diurnal mammals are more likely to be monogamous than nocturnal mammals, while arboreal mammals tend to have a smaller litter size than terrestrial mammals. Coevolution between diet and the seasonal breeding behavior test shows that year-round breeding preceded the dietary change to omnivory, while seasonal breeding preceded the dietary change to carnivory. We also discuss the evolution of reproductive strategy of mammals. Genes selected as predictors were identified as well; for example, genes function as tumor suppressor were selected as predictors of weaning age.
format Online
Article
Text
id pubmed-8157036
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-81570362021-05-28 Evolution of Reproductive Life History in Mammals and the Associated Change of Functional Constraints Wu, Jiaqi Yonezawa, Takahiro Kishino, Hirohisa Genes (Basel) Article Phylogenetic trees based on multiple genomic loci enable us to estimate the evolution of functional constraints that operate on genes based on lineage-specific fluctuation of the evolutionary rate at particular gene loci, “gene–branch interactions”. Using this information as predictors, our previous work inferred that the common ancestor of placental mammals was nocturnal, insectivorous, solitary, and bred seasonally. Here, we added seven new continuous traits including lifespan, bodyweight, and five reproduction-related traits and inferred the coevolution network of 14 core life history traits for 89 mammals. In this network, bodyweight and lifespan are not directly connected to each other; instead, their correlation is due to both of them coevolving with gestation period. Diurnal mammals are more likely to be monogamous than nocturnal mammals, while arboreal mammals tend to have a smaller litter size than terrestrial mammals. Coevolution between diet and the seasonal breeding behavior test shows that year-round breeding preceded the dietary change to omnivory, while seasonal breeding preceded the dietary change to carnivory. We also discuss the evolution of reproductive strategy of mammals. Genes selected as predictors were identified as well; for example, genes function as tumor suppressor were selected as predictors of weaning age. MDPI 2021-05-14 /pmc/articles/PMC8157036/ /pubmed/34068942 http://dx.doi.org/10.3390/genes12050740 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Wu, Jiaqi
Yonezawa, Takahiro
Kishino, Hirohisa
Evolution of Reproductive Life History in Mammals and the Associated Change of Functional Constraints
title Evolution of Reproductive Life History in Mammals and the Associated Change of Functional Constraints
title_full Evolution of Reproductive Life History in Mammals and the Associated Change of Functional Constraints
title_fullStr Evolution of Reproductive Life History in Mammals and the Associated Change of Functional Constraints
title_full_unstemmed Evolution of Reproductive Life History in Mammals and the Associated Change of Functional Constraints
title_short Evolution of Reproductive Life History in Mammals and the Associated Change of Functional Constraints
title_sort evolution of reproductive life history in mammals and the associated change of functional constraints
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157036/
https://www.ncbi.nlm.nih.gov/pubmed/34068942
http://dx.doi.org/10.3390/genes12050740
work_keys_str_mv AT wujiaqi evolutionofreproductivelifehistoryinmammalsandtheassociatedchangeoffunctionalconstraints
AT yonezawatakahiro evolutionofreproductivelifehistoryinmammalsandtheassociatedchangeoffunctionalconstraints
AT kishinohirohisa evolutionofreproductivelifehistoryinmammalsandtheassociatedchangeoffunctionalconstraints