Intrinsic signal amplification by type III CRISPR-Cas systems provides a sequence-specific SARS-CoV-2 diagnostic

There is an urgent need for inexpensive new technologies that enable fast, reliable, and scalable detection of viruses. Here, we repurpose the type III CRISPR-Cas system for sensitive and sequence-specific detection of SARS-CoV-2. RNA recognition by the type III CRISPR complex triggers Cas10-mediate...

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Detalles Bibliográficos
Autores principales: Santiago-Frangos, Andrew, Hall, Laina N., Nemudraia, Anna, Nemudryi, Artem, Krishna, Pushya, Wiegand, Tanner, Wilkinson, Royce A., Snyder, Deann T., Hedges, Jodi F., Cicha, Calvin, Lee, Helen H., Graham, Ava, Jutila, Mark A., Taylor, Matthew P., Wiedenheft, Blake
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157118/
https://www.ncbi.nlm.nih.gov/pubmed/34075364
http://dx.doi.org/10.1016/j.xcrm.2021.100319

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