Valproic Acid Suppresses Autoimmune Recurrence and Allograft Rejection in Islet Transplantation through Induction of the Differentiation of Regulatory T Cells and Can Be Used in Cell Therapy for Type 1 Diabetes

Type 1 diabetes mellitus (T1D) results from the destruction of insulin-producing β cells in the islet of the pancreas by lymphocytes. Non-obese diabetic (NOD) mouse is an animal model frequently used for this disease. It has been considered that T1D is a T cell-mediated autoimmune disease. Both CD4+...

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Detalles Bibliográficos
Autores principales: Lin, Jeng-Rong, Huang, Shing-Hwa, Wu, Chih-Hsiung, Chen, Yuan-Wu, Hong, Zhi-Jie, Cheng, Chia-Pi, Sytwu, Huey-Kang, Lin, Gu-Jiun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157191/
https://www.ncbi.nlm.nih.gov/pubmed/34067829
http://dx.doi.org/10.3390/ph14050475

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