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KRAS Mutation Dictates the Cancer Immune Environment in Pancreatic Ductal Adenocarcinoma and Other Adenocarcinomas

SIMPLE SUMMARY: The vast majority of patients with pancreatic ductal adenocarcinomas harbor KRAS mutations in their tumors. Functionally, mutated KRAS is not only dedicated to tumor cell proliferation, survival and invasiveness, but also causing the immunosuppression in this cancer. In this situatio...

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Detalles Bibliográficos
Autores principales: Gu, Meichen, Gao, Yanli, Chang, Pengyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157241/
https://www.ncbi.nlm.nih.gov/pubmed/34069772
http://dx.doi.org/10.3390/cancers13102429