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Unravelling the effect of N(ε)-(carboxyethyl)lysine on the conformation, dynamics and aggregation propensity of α-synuclein

α-Synuclein (αS) aggregation is a hallmark in several neurodegenerative diseases. Among them, Parkinson's disease is highlighted, characterized by the intraneuronal deposition of Lewy bodies (LBs) which causes the loss of dopaminergic neurons. αS is the main component of LBs and in them, it usu...

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Detalles Bibliográficos
Autores principales:	Mariño, Laura, Ramis, Rafael, Casasnovas, Rodrigo, Ortega-Castro, Joaquín, Vilanova, Bartolomé, Frau, Juan, Adrover, Miquel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2020
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157327/ https://www.ncbi.nlm.nih.gov/pubmed/34122841 http://dx.doi.org/10.1039/d0sc00906g

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