Cargando…

Prediction of Grade Reclassification of Prostate Cancer Patients on Active Surveillance through the Combination of a Three-miRNA Signature and Selected Clinical Variables

SIMPLE SUMMARY: Active surveillance (AS) has evolved as an alternative to radical treatment for potentially indolent prostate cancer. However, current selection criteria for entering AS are suboptimal, and a significant percentage of patients discontinue AS because of disease reclassification. Hence...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gandellini, Paolo, Ciniselli, Chiara Maura, Rancati, Tiziana, Marenghi, Cristina, Doldi, Valentina, El Bezawy, Rihan, Lecchi, Mara, Claps, Melanie, Catanzaro, Mario, Avuzzi, Barbara, Campi, Elisa, Colecchia, Maurizio, Badenchini, Fabio, Verderio, Paolo, Valdagni, Riccardo, Zaffaroni, Nadia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157371/ https://www.ncbi.nlm.nih.gov/pubmed/34069838 http://dx.doi.org/10.3390/cancers13102433

Ejemplares similares

Potential of the Stromal Matricellular Protein Periostin as a Biomarker to Improve Risk Assessment in Prostate Cancer
por: Doldi, Valentina, et al.
Publicado: (2022)

miR-205 enhances radiation sensitivity of prostate cancer cells by impairing DNA damage repair through PKCε and ZEB1 inhibition
por: El Bezawy, Rihan, et al.
Publicado: (2019)

miR-1272 Exerts Tumor-Suppressive Functions in Prostate Cancer via HIP1 Suppression
por: Rotundo, Federica, et al.
Publicado: (2020)

miR-550a-3p is a prognostic biomarker and exerts tumor-suppressive functions by targeting HSP90AA1 in diffuse malignant peritoneal mesothelioma
por: El Bezawy, Rihan, et al.
Publicado: (2022)

SPOP Deregulation Improves the Radiation Response of Prostate Cancer Models by Impairing DNA Damage Repair
por: El Bezawy, Rihan, et al.
Publicado: (2020)

MicroRNAs as Epigenetic Determinants of Treatment Response and Potential Therapeutic Targets in Prostate Cancer
por: Doldi, Valentina, et al.
Publicado: (2021)

Integrated gene and miRNA expression analysis of prostate cancer associated fibroblasts supports a prominent role for interleukin-6 in fibroblast activation
por: Doldi, Valentina, et al.
Publicado: (2015)

3Rs Principle and Legislative Decrees to Achieve High Standard of Animal Research
por: Verderio, Paolo, et al.
Publicado: (2023)

Supporting Patients With Untreated Prostate Cancer on Active Surveillance: What Causes an Increase in Anxiety During the First 10 Months?
por: Alvisi, Maria Francesca, et al.
Publicado: (2020)

Stability of Multi-Parametric Prostate MRI Radiomic Features to Variations in Segmentation
por: Thulasi Seetha, Sithin, et al.
Publicado: (2023)

Developing miRNA signatures: a multivariate prospective
por: Verderio, Paolo, et al.
Publicado: (2016)

Antitumor activity of miR-34a in peritoneal mesothelioma relies on c-MET and AXL inhibition: persistent activation of ERK and AKT signaling as a possible cytoprotective mechanism
por: El Bezawy, Rihan, et al.
Publicado: (2017)

Comment on ‘Circulating cell-free miRNAs as biomarker for triple-negative breast cancer'—Methodological challenges in combining miRNAs as circulating biomarkers
por: Verderio, P, et al.
Publicado: (2016)

miR-34a-Mediated Survivin Inhibition Improves the Antitumor Activity of Selinexor in Triple-Negative Breast Cancer
por: Martini, Silvia, et al.
Publicado: (2021)

Eleven-year Management of Prostate Cancer Patients on Active Surveillance: What have We Learned?
por: Marenghi, Cristina, et al.
Publicado: (2017)

COVID-19 Vaccination in Health Care Workers in Italy: A Literature Review and a Report from a Comprehensive Cancer Center
por: Ciniselli, Chiara Maura, et al.
Publicado: (2022)

Evaluation of Mediators Associated with the Inflammatory Response in Prostate Cancer Patients Undergoing Radiotherapy
por: Bedini, Nice, et al.
Publicado: (2018)

Gene signatures of circulating breast cancer cell models are a source of novel molecular determinants of metastasis and improve circulating tumor cell detection in patients
por: Fina, Emanuela, et al.
Publicado: (2022)

LEADeR role of miR-205 host gene as long noncoding RNA in prostate basal cell differentiation
por: Profumo, Valentina, et al.
Publicado: (2019)

miR-21: an oncomir on strike in prostate cancer
por: Folini, Marco, et al.
Publicado: (2010)

Circulating miRNAs as Novel Non-Invasive Biomarkers to Aid the Early Diagnosis of Suspicious Breast Lesions for Which Biopsy Is Recommended
por: Giussani, Marta, et al.
Publicado: (2021)

Cross-cultural differences in men on active surveillance’ anxiety: a longitudinal comparison between Italian and Dutch patients from the Prostate cancer Research International Active Surveillance study
por: Dordoni, Paola, et al.
Publicado: (2022)

Patient-reported outcome measurements in post-mastectomy implant-based breast reconstruction and radiotherapy: Analysis of BREAST-Q data
por: Sala, Laura, et al.
Publicado: (2022)

Data and performances evaluation of the SPIDIA-DNA Pan-European External Quality Assessment: 2nd SPIDIA-DNA laboratory report
por: Malentacchi, Francesca, et al.
Publicado: (2016)

Editorial: Modeling for Prediction of Radiation-Induced Toxicity to Improve Therapeutic Ratio in the Modern Radiation Therapy Era
por: Rancati, Tiziana, et al.
Publicado: (2021)

Multiparametric Analysis of Cell-Free DNA in Melanoma Patients
por: Salvianti, Francesca, et al.
Publicado: (2012)

Anti-tumor activity of selective inhibitors of XPO1/CRM1-mediated nuclear export in diffuse malignant peritoneal mesothelioma: the role of survivin
por: De Cesare, Michelandrea, et al.
Publicado: (2015)

1647TiP Antiandrogen therapy and TMPRSS2 status: How prostate cancer patients are protected from COVID-19 pandemic
por: Claps, M., et al.
Publicado: (2021)

COVID‐19 outbreak in Lombardy: Impact on reducing solid cancer diagnoses in 2020
por: Trama, Annalisa, et al.
Publicado: (2022)

What if the future of HER2‐positive breast cancer patients was written in miRNAs? An exploratory analysis from NeoALTTO study
por: Pizzamiglio, Sara, et al.
Publicado: (2021)

Hereditary colorectal cancer syndromes and the COVID-19 pandemic: results from a survey conducted in patients enrolled in a dedicated registry
por: Signoroni, Stefano, et al.
Publicado: (2021)

Semantic reclassification of the UMLS concepts
por: Fan, Jung-Wei, et al.
Publicado: (2008)

Thematic Reclassifications and Emerging Sciences
por: Sandoz, Raphaël
Publicado: (2021)

Rhizomal Reclassification of Living Organisms
por: Ibrahim, Ahmad, et al.
Publicado: (2021)

miR-380-5p-mediated repression of TEP1 and TSPYL5 interferes with telomerase activity and favours the emergence of an “ALT-like” phenotype in diffuse malignant peritoneal mesothelioma cells
por: Cimino-Reale, Graziella, et al.
Publicado: (2017)

SARS-CoV-2 Serology Monitoring of a Cancer Center Staff in the Pandemic Most Infected Italian Region
por: Ciniselli, Chiara Maura, et al.
Publicado: (2021)

MIR205HG/LEADR Long Noncoding RNA Binds to Primed Proximal Regulatory Regions in Prostate Basal Cells Through a Triplex- and Alu-Mediated Mechanism
por: Bezzecchi, Eugenia, et al.
Publicado: (2022)

Inter-observer variability in contouring the penile bulb on CT images for prostate cancer treatment planning
por: Perna, Lucia, et al.
Publicado: (2011)

Stilbosporaceae resurrected: generic reclassification and speciation
por: Voglmayr, H., et al.
Publicado: (2014)

Editorial: Monogenic vs. Oligogenic Reclassification
por: Messaoud, Olfa, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_itmugr3heo3e0n98bg10agalct