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MicroRNA-449a delays lung cancer development through inhibiting KDM3A/HIF-1α axis
BACKGROUND: It has been established that microRNA (miR)-449a is anti-tumorigenic in cancers, including lung cancer. Therefore, this study further explored miR-449a-mediated mechanism in lung cancer, mainly focusing on lysine demethylase 3A/hypoxia-induced factor-1α (KDM3A/HIF-1α) axis. METHODS: miR-...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157436/ https://www.ncbi.nlm.nih.gov/pubmed/34044859 http://dx.doi.org/10.1186/s12967-021-02881-8 |