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Dearomatization of aryl sulfoxides: a switch between mono- and dual-difluoroalkylation

Herein we describe the dearomatization of aryl sulfoxides with difluoroenol silyl ether (DFESE) using a rearrangement/addition protocol. The selection of the sulfoxide activator determines whether one or two difluoroalkyl groups are incorporated into dearomatized products. Using TFAA can deliberatel...

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Detalles Bibliográficos
Autores principales:	Huang, Xin, Zhang, Yage, Liang, Weijian, Zhang, Qifeng, Zhan, Yaling, Kong, Lichun, Peng, Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2020
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157523/ https://www.ncbi.nlm.nih.gov/pubmed/34122809 http://dx.doi.org/10.1039/d0sc00244e

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