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Probing enzymatic activity – a radical approach

Deubiquitinating enzymes (DUBs) are known to have numerous important interactions with the ubiquitin cascade and their dysregulation is associated with several diseases, including cancer and neurodegeneration. They are an important class of enzyme, and activity-based probes have been developed as an...

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Detalles Bibliográficos
Autores principales: Taylor, Neil C., Hessman, Gary, Kramer, Holger B., McGouran, Joanna F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157568/
https://www.ncbi.nlm.nih.gov/pubmed/34122797
http://dx.doi.org/10.1039/c9sc05258e

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