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Probing enzymatic activity – a radical approach
Deubiquitinating enzymes (DUBs) are known to have numerous important interactions with the ubiquitin cascade and their dysregulation is associated with several diseases, including cancer and neurodegeneration. They are an important class of enzyme, and activity-based probes have been developed as an...
Autores principales: | Taylor, Neil C., Hessman, Gary, Kramer, Holger B., McGouran, Joanna F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157568/ https://www.ncbi.nlm.nih.gov/pubmed/34122797 http://dx.doi.org/10.1039/c9sc05258e |
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