Cargando…

Phthalates and Their Impacts on Human Health

Phthalates are a series of widely used chemicals that demonstrate to be endocrine disruptors and are detrimental to human health. Phthalates can be found in most products that have contact with plastics during producing, packaging, or delivering. Despite the short half-lives in tissues, chronic expo...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yufei, Qian, Haifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157593/
https://www.ncbi.nlm.nih.gov/pubmed/34069956
http://dx.doi.org/10.3390/healthcare9050603
_version_ 1783699717204475904
author Wang, Yufei
Qian, Haifeng
author_facet Wang, Yufei
Qian, Haifeng
author_sort Wang, Yufei
collection PubMed
description Phthalates are a series of widely used chemicals that demonstrate to be endocrine disruptors and are detrimental to human health. Phthalates can be found in most products that have contact with plastics during producing, packaging, or delivering. Despite the short half-lives in tissues, chronic exposure to phthalates will adversely influence the endocrine system and functioning of multiple organs, which has negative long-term impacts on the success of pregnancy, child growth and development, and reproductive systems in both young children and adolescents. Several countries have established restrictions and regulations on some types of phthalates; however, we think that more countries should establish constraints or substitute measures for phthalates to reduce health risks. This article aims to summarize the adverse impacts of phthalates on human health, analyze the toxicity mechanism, assess the risks, and finally provide feasible strategies to reduce exposure of the public to phthalates.
format Online
Article
Text
id pubmed-8157593
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-81575932021-05-28 Phthalates and Their Impacts on Human Health Wang, Yufei Qian, Haifeng Healthcare (Basel) Review Phthalates are a series of widely used chemicals that demonstrate to be endocrine disruptors and are detrimental to human health. Phthalates can be found in most products that have contact with plastics during producing, packaging, or delivering. Despite the short half-lives in tissues, chronic exposure to phthalates will adversely influence the endocrine system and functioning of multiple organs, which has negative long-term impacts on the success of pregnancy, child growth and development, and reproductive systems in both young children and adolescents. Several countries have established restrictions and regulations on some types of phthalates; however, we think that more countries should establish constraints or substitute measures for phthalates to reduce health risks. This article aims to summarize the adverse impacts of phthalates on human health, analyze the toxicity mechanism, assess the risks, and finally provide feasible strategies to reduce exposure of the public to phthalates. MDPI 2021-05-18 /pmc/articles/PMC8157593/ /pubmed/34069956 http://dx.doi.org/10.3390/healthcare9050603 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Wang, Yufei
Qian, Haifeng
Phthalates and Their Impacts on Human Health
title Phthalates and Their Impacts on Human Health
title_full Phthalates and Their Impacts on Human Health
title_fullStr Phthalates and Their Impacts on Human Health
title_full_unstemmed Phthalates and Their Impacts on Human Health
title_short Phthalates and Their Impacts on Human Health
title_sort phthalates and their impacts on human health
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157593/
https://www.ncbi.nlm.nih.gov/pubmed/34069956
http://dx.doi.org/10.3390/healthcare9050603
work_keys_str_mv AT wangyufei phthalatesandtheirimpactsonhumanhealth
AT qianhaifeng phthalatesandtheirimpactsonhumanhealth