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Tubule-specific protein nanocages potentiate targeted renal fibrosis therapy

BACKGROUND: Despite the dramatic advances in modern medicine, efficient therapeutic measures for renal fibrosis remain limited. Celastrol (CLT) is effective in treating renal fibrosis in rat models, while causing severe systemic toxicity. Thus, we designed a tubule-specific nanocage (K3-HBc NCs) tha...

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Detalles Bibliográficos
Autores principales:	Zhang, Xuan, Chen, Qian, Zhang, Liyuan, Zheng, Haiping, Lin, Chunjie, Yang, Qunfang, Liu, Tao, Zhang, Haigang, Chen, Xiaohong, Ren, Lei, Shan, Wenjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157627/ https://www.ncbi.nlm.nih.gov/pubmed/34039349 http://dx.doi.org/10.1186/s12951-021-00900-w

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