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Temporal trends in heart failure mortality in an integrated healthcare delivery system, California, and the US, 2001–2017

BACKGROUND: In recent years, decreases in mortality rates attributable to cardiovascular diseases have slowed but mortality attributable to heart failure (HF) has increased. METHODS: Between 2001–2017, trends in age-adjusted mortality with HF as an underlying cause for Kaiser Permanente Southern Cal...

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Autores principales: Mefford, Matthew T., Zhuang, Zimin, Liang, Zhi, Chen, Wansu, Koyama, Sandra Y., Taitano, Maria T., Watson, Heather L., Lee, Ming-Sum, Sidney, Stephen, Reynolds, Kristi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157708/
https://www.ncbi.nlm.nih.gov/pubmed/34039262
http://dx.doi.org/10.1186/s12872-021-02075-6
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author Mefford, Matthew T.
Zhuang, Zimin
Liang, Zhi
Chen, Wansu
Koyama, Sandra Y.
Taitano, Maria T.
Watson, Heather L.
Lee, Ming-Sum
Sidney, Stephen
Reynolds, Kristi
author_facet Mefford, Matthew T.
Zhuang, Zimin
Liang, Zhi
Chen, Wansu
Koyama, Sandra Y.
Taitano, Maria T.
Watson, Heather L.
Lee, Ming-Sum
Sidney, Stephen
Reynolds, Kristi
author_sort Mefford, Matthew T.
collection PubMed
description BACKGROUND: In recent years, decreases in mortality rates attributable to cardiovascular diseases have slowed but mortality attributable to heart failure (HF) has increased. METHODS: Between 2001–2017, trends in age-adjusted mortality with HF as an underlying cause for Kaiser Permanente Southern California (KPSC) members were derived through linkage with state death files and compared with trends among California residents and the US. Average annual percent change (AAPC) and 95% confidence intervals (CI) were calculated using Joinpoint regression. Analyses were repeated examining HF as a contributing cause of death. RESULTS: In KPSC, the age-adjusted HF mortality rates were comparable to California but lower than the US, increasing from 23.9 per 100,000 person-years (PY) in 2001 to 44.7 per 100,000 PY in 2017, representing an AAPC of 1.3% (95% CI 0.0%, 2.6%). HF mortality also increased in California from 33.9 to 46.5 per 100,000 PY (AAPC 1.5%, 95% CI 0.3%, 2.7%), while remaining unchanged in the US at 57.9 per 100,000 PY in 2001 and 2017 (AAPC 0.0%, 95% CI − 0.5%, 0.5%). Trends among KPSC members ≥ 65 years old were similar to the overall population, while trends among members 45–64 years old were flat between 2001–2017. Small changes in mortality with HF as a contributing cause were observed in KPSC members between 2001 and 2017, which differed from California and the US. CONCLUSION: Lower rates of HF mortality were observed in KPSC compared to the US. Given the aging of the US population and increasing prevalence of HF, it will be important to examine individual and care-related factors driving susceptibility to HF mortality. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12872-021-02075-6.
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spelling pubmed-81577082021-05-28 Temporal trends in heart failure mortality in an integrated healthcare delivery system, California, and the US, 2001–2017 Mefford, Matthew T. Zhuang, Zimin Liang, Zhi Chen, Wansu Koyama, Sandra Y. Taitano, Maria T. Watson, Heather L. Lee, Ming-Sum Sidney, Stephen Reynolds, Kristi BMC Cardiovasc Disord Research Article BACKGROUND: In recent years, decreases in mortality rates attributable to cardiovascular diseases have slowed but mortality attributable to heart failure (HF) has increased. METHODS: Between 2001–2017, trends in age-adjusted mortality with HF as an underlying cause for Kaiser Permanente Southern California (KPSC) members were derived through linkage with state death files and compared with trends among California residents and the US. Average annual percent change (AAPC) and 95% confidence intervals (CI) were calculated using Joinpoint regression. Analyses were repeated examining HF as a contributing cause of death. RESULTS: In KPSC, the age-adjusted HF mortality rates were comparable to California but lower than the US, increasing from 23.9 per 100,000 person-years (PY) in 2001 to 44.7 per 100,000 PY in 2017, representing an AAPC of 1.3% (95% CI 0.0%, 2.6%). HF mortality also increased in California from 33.9 to 46.5 per 100,000 PY (AAPC 1.5%, 95% CI 0.3%, 2.7%), while remaining unchanged in the US at 57.9 per 100,000 PY in 2001 and 2017 (AAPC 0.0%, 95% CI − 0.5%, 0.5%). Trends among KPSC members ≥ 65 years old were similar to the overall population, while trends among members 45–64 years old were flat between 2001–2017. Small changes in mortality with HF as a contributing cause were observed in KPSC members between 2001 and 2017, which differed from California and the US. CONCLUSION: Lower rates of HF mortality were observed in KPSC compared to the US. Given the aging of the US population and increasing prevalence of HF, it will be important to examine individual and care-related factors driving susceptibility to HF mortality. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12872-021-02075-6. BioMed Central 2021-05-26 /pmc/articles/PMC8157708/ /pubmed/34039262 http://dx.doi.org/10.1186/s12872-021-02075-6 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Mefford, Matthew T.
Zhuang, Zimin
Liang, Zhi
Chen, Wansu
Koyama, Sandra Y.
Taitano, Maria T.
Watson, Heather L.
Lee, Ming-Sum
Sidney, Stephen
Reynolds, Kristi
Temporal trends in heart failure mortality in an integrated healthcare delivery system, California, and the US, 2001–2017
title Temporal trends in heart failure mortality in an integrated healthcare delivery system, California, and the US, 2001–2017
title_full Temporal trends in heart failure mortality in an integrated healthcare delivery system, California, and the US, 2001–2017
title_fullStr Temporal trends in heart failure mortality in an integrated healthcare delivery system, California, and the US, 2001–2017
title_full_unstemmed Temporal trends in heart failure mortality in an integrated healthcare delivery system, California, and the US, 2001–2017
title_short Temporal trends in heart failure mortality in an integrated healthcare delivery system, California, and the US, 2001–2017
title_sort temporal trends in heart failure mortality in an integrated healthcare delivery system, california, and the us, 2001–2017
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157708/
https://www.ncbi.nlm.nih.gov/pubmed/34039262
http://dx.doi.org/10.1186/s12872-021-02075-6
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