Cargando…

Up-regulation of long non-coding RNA CYTOR induced by icariin promotes the viability and inhibits the apoptosis of chondrocytes

BACKGROUND: Icariin (ICAR) is the main effective component extracted from epimedium, and is reported to have the potential to treat osteoarthritis (OA). However, its pharmacological function on chondrocytes has not been fully clarified. METHODS: Different doses of ICAR were used to treat chondrocyte...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Guoyou, Zhang, Lei, Shen, Huarui, Hao, Qi, Fu, Shijie, Liu, Xia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157716/ https://www.ncbi.nlm.nih.gov/pubmed/34039336 http://dx.doi.org/10.1186/s12906-021-03322-1

Ejemplares similares

The long non-coding RNA CYTOR drives colorectal cancer progression by interacting with NCL and Sam68
por: Wang, Xue, et al.
Publicado: (2018)

Icariin inhibits chondrocyte apoptosis and angiogenesis by regulating the TDP‐43 signaling pathway
por: Huang, He, et al.
Publicado: (2019)

Circulating CYTOR as a Potential Biomarker in Breast Cancer
por: Moradi, Mohammad-Taher, et al.
Publicado: (2020)

Role of IFT88 in icariin-regulated maintenance of the chondrocyte phenotype
por: Xiang, Wei, et al.
Publicado: (2018)

Icariin Activates Autophagy via Down-Regulation of the NF-κB Signaling-Mediated Apoptosis in Chondrocytes
por: Mi, Bobin, et al.
Publicado: (2018)

Icariin protects vertebral endplate chondrocytes against apoptosis and degeneration via activating Nrf-2/HO-1 pathway
por: Shao, Yuandong, et al.
Publicado: (2022)

Long non-coding RNA (lncRNA) CYTOR promotes hepatocellular carcinoma proliferation by targeting the microRNA-125a-5p/LASP1 axis
por: Liu, Yadong, et al.
Publicado: (2022)

CYTOR drives prostate cancer progression via facilitating AR‐V7 generation and its oncogenic signalling
por: Yu, Jianpeng, et al.
Publicado: (2023)

Icariin Improves the Viability and Function of Cryopreserved Human Nucleus Pulposus-Derived Mesenchymal Stem Cells
por: Chen, Sheng, et al.
Publicado: (2018)

Long noncoding RNA CYTOR sponges miR-195 to modulate proliferation, migration, invasion and radiosensitivity in nonsmall cell lung cancer cells
por: Zhang, Jun, et al.
Publicado: (2018)

P608: THE EXPRESSION OF CYTOR LNCRNA HAS POOR PROGNOSTIC VALUE IN CLL PATIENTS AND IS ASSOCIATED WITH MICROENVIRONMENTAL STIMULI.
por: Hernández, Lluís, et al.
Publicado: (2023)

Importance Of Donor Chondrocyte Viability in Osteochondral Allografting
por: Stannard, James P., et al.
Publicado: (2015)

Flavonoid Compound Icariin Activates Hypoxia Inducible Factor-1α in Chondrocytes and Promotes Articular Cartilage Repair
por: Wang, Pengzhen, et al.
Publicado: (2016)

Icariin Alleviates IL-1β-Induced Matrix Degradation By Activating The Nrf2/ARE Pathway In Human Chondrocytes
por: Zuo, Shi, et al.
Publicado: (2019)

Icariin alleviates osteoarthritis by regulating autophagy of chondrocytes by mediating PI3K/AKT/mTOR signaling
por: Tang, Yanghua, et al.
Publicado: (2021)

LncRNA CYTOR affects the proliferation, cell cycle and apoptosis of hepatocellular carcinoma cells by regulating the miR-125b-5p/KIAA1522 axis
por: Hu, Bo, et al.
Publicado: (2020)

ENO2 Promotes Colorectal Cancer Metastasis by Interacting with the LncRNA CYTOR and Activating YAP1-Induced EMT
por: Lv, Chunwei, et al.
Publicado: (2022)

lncRNA cytoskeleton regulator RNA (CYTOR): Diverse functions in metabolism, inflammation and tumorigenesis, and potential applications in precision oncology
por: Ou, Chunlin, et al.
Publicado: (2021)

Icariin inhibits the inflammation through down-regulating NF-κB/HIF-2α signal pathways in chondrocytes
por: Wang, Pengzhen, et al.
Publicado: (2020)

The Long Noncoding RNA Cytoskeleton Regulator RNA (CYTOR)/miRNA-24-3p Axis Facilitates Nasopharyngeal Carcinoma Progression by Modulating GAD1 Expression
por: Du, Jingwei, et al.
Publicado: (2023)

The human umbilical cord stem cells improve the viability of OA degenerated chondrocytes
por: Wang, Hao, et al.
Publicado: (2018)

Hydrostatic Compress Force Enhances the Viability and Decreases the Apoptosis of Condylar Chondrocytes through Integrin-FAK-ERK/PI3K Pathway
por: Ma, Dandan, et al.
Publicado: (2016)

Membrane-seeded autologous chondrocytes: cell viability and characterization at surgery
por: Gigante, Antonio, et al.
Publicado: (2006)

lncRNA CYTOR promotes tamoxifen resistance in breast cancer cells via sponging miR-125a-5p
por: Liu, Yungyong, et al.
Publicado: (2020)

Effects of Icariin on Reproductive Functions in Male Rats
por: Chen, Maoxin, et al.
Publicado: (2014)

The endoplasmic reticulum stress induced by tunicamycin affects the viability and autophagy activity of chondrocytes
por: Wu, Hao, et al.
Publicado: (2020)

Icariin improves cognitive impairment by inhibiting ferroptosis of nerve cells
por: Yang, Yang, et al.
Publicado: (2023)

The protective effect of icariin and phosphorylated icariin against LPS-induced intestinal goblet cell dysfunction
por: Xiong, Wen, et al.
Publicado: (2019)

Factors associated with 90-day acute ischemic stroke in patients ≥70 years old with total hip arthroplasty for hip fracture
por: He, Rui, et al.
Publicado: (2022)

Icariin induces apoptosis by suppressing autophagy in tamoxifen-resistant breast cancer cell line MCF-7/TAM
por: Cheng, Xia, et al.
Publicado: (2019)

lncRNA CYTOR promotes aberrant glycolysis and mitochondrial respiration via HNRNPC-mediated ZEB1 stabilization in oral squamous cell carcinoma
por: Zhu, Weiwen, et al.
Publicado: (2022)

Viability of Pathologic Cartilage Fragments as a Source for Autologous Chondrocyte Cultures
por: Guillén-García, Pedro, et al.
Publicado: (2015)

In Vivo Toxicity of Local Anesthetics and Corticosteroids on Chondrocyte and Synoviocyte Viability and Metabolism
por: Sherman, Seth L., et al.
Publicado: (2015)

In Vitro Toxicity of Local Anesthetics and Corticosteroids on Chondrocyte and Synoviocyte Viability and Metabolism
por: Sherman, Seth L., et al.
Publicado: (2015)

HIF-1α had Pivotal Effects on Downregulation of miR-210 Decreasing Viability and Inducing Apoptosis in Hypoxic Chondrocytes
por: Chang, Zhiqiang, et al.
Publicado: (2014)

Co-implantation of bone marrow mesenchymal stem cells and chondrocytes increase the viability of chondrocytes in rat osteo-chondral defects
por: Zhao, Zhi, et al.
Publicado: (2018)

Expression of long non-coding RNAs in chondrocytes from proximal interphalangeal joints
por: Lv, Dong, et al.
Publicado: (2017)

Chondrocyte Apoptosis in the Pathogenesis of Osteoarthritis
por: Hwang, Hyun Sook, et al.
Publicado: (2015)

Icariin Metabolism by Human Intestinal Microflora
por: Wu, Hailong, et al.
Publicado: (2016)

Icariin Induced B16 Melanoma Tumor Cells Apoptosis, Suppressed Tumor Growth and Metastasis
por: LI, Xiuying, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_1lfe26aljnfa3tpkkuj14velo9