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Safety and efficacy profile of mogamulizumab (Poteligeo) in the treatment of cancers: an update evidence from 14 studies
BACKGROUND: CC chemokine receptor 4 (CCR4), the receptor for CCL22 and CCL17, is expressed on the surface of effector Tregs that have the highest suppressive effects on antitumor immune response. CCR4 is also widely expressed on the surface of tumor cells from patients with adult T-cell leukemia/lym...
Autores principales: | Zhang, Ting, Sun, Jing, Li, Jinying, Zhao, Yunuo, Zhang, Tao, Yang, Ruoning, Ma, Xuelei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157723/ https://www.ncbi.nlm.nih.gov/pubmed/34039310 http://dx.doi.org/10.1186/s12885-021-08363-w |
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