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Global, regional and national burden of anxiety disorders from 1990 to 2019: results from the Global Burden of Disease Study 2019

AIMS: Anxiety disorders are widespread across the world. A systematic understanding of the disease burden, temporal trend and risk factors of anxiety disorders provides the essential foundation for targeted public policies on mental health at the national, regional, and global levels. METHODS: The e...

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Autores principales: Yang, Xiaorong, Fang, Yuan, Chen, Hui, Zhang, Tongchao, Yin, Xiaolin, Man, Jinyu, Yang, Lejin, Lu, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157816/
https://www.ncbi.nlm.nih.gov/pubmed/33955350
http://dx.doi.org/10.1017/S2045796021000275
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author Yang, Xiaorong
Fang, Yuan
Chen, Hui
Zhang, Tongchao
Yin, Xiaolin
Man, Jinyu
Yang, Lejin
Lu, Ming
author_facet Yang, Xiaorong
Fang, Yuan
Chen, Hui
Zhang, Tongchao
Yin, Xiaolin
Man, Jinyu
Yang, Lejin
Lu, Ming
author_sort Yang, Xiaorong
collection PubMed
description AIMS: Anxiety disorders are widespread across the world. A systematic understanding of the disease burden, temporal trend and risk factors of anxiety disorders provides the essential foundation for targeted public policies on mental health at the national, regional, and global levels. METHODS: The estimation of anxiety disorders in the Global Burden of Disease Study 2019 using systematic review was conducted to describe incidence, prevalence and disability-adjusted life years (DALYs) in 204 countries and regions from 1990 to 2019. We calculated the estimated annual percentage change (EAPC) to quantify the temporal trends in anxiety disorders burden by sex, region and age over the past 30 years and analysed the impact of epidemiological and demographic changes on anxiety disorders. RESULTS: Globally, 45.82 [95% uncertainty interval (UI): 37.14, 55.62] million incident cases of anxiety disorders, 301.39 million (95% UI: 252.63, 356.00) prevalent cases and 28.68 (95% UI: 19.86, 39.32) million DALYs were estimated in 2019. Although the overall age-standardised burden rate of anxiety disorders remained stable over the past three decades, the latest absolute number of anxiety disorders increased by 50% from 1990. We observed huge disparities in both age-standardised burden rate and changing trend of anxiety disorders in sex, country and age. In 2019, 7.07% of the global DALYs due to anxiety disorders were attributable to bullying victimisation, mainly among the population aged 5–39 years, and the proportion increased in almost all countries and territories compared with 1990. CONCLUSION: Anxiety disorder is still the most common mental illness in the world and has a striking impact on the global burden of disease. Controlling potential risk factors, such as bullying, establishing effective mental health knowledge dissemination and diversifying intervention strategies adapted to specific characteristics will reduce the burden of anxiety disorders.
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spelling pubmed-81578162021-06-07 Global, regional and national burden of anxiety disorders from 1990 to 2019: results from the Global Burden of Disease Study 2019 Yang, Xiaorong Fang, Yuan Chen, Hui Zhang, Tongchao Yin, Xiaolin Man, Jinyu Yang, Lejin Lu, Ming Epidemiol Psychiatr Sci Original Article AIMS: Anxiety disorders are widespread across the world. A systematic understanding of the disease burden, temporal trend and risk factors of anxiety disorders provides the essential foundation for targeted public policies on mental health at the national, regional, and global levels. METHODS: The estimation of anxiety disorders in the Global Burden of Disease Study 2019 using systematic review was conducted to describe incidence, prevalence and disability-adjusted life years (DALYs) in 204 countries and regions from 1990 to 2019. We calculated the estimated annual percentage change (EAPC) to quantify the temporal trends in anxiety disorders burden by sex, region and age over the past 30 years and analysed the impact of epidemiological and demographic changes on anxiety disorders. RESULTS: Globally, 45.82 [95% uncertainty interval (UI): 37.14, 55.62] million incident cases of anxiety disorders, 301.39 million (95% UI: 252.63, 356.00) prevalent cases and 28.68 (95% UI: 19.86, 39.32) million DALYs were estimated in 2019. Although the overall age-standardised burden rate of anxiety disorders remained stable over the past three decades, the latest absolute number of anxiety disorders increased by 50% from 1990. We observed huge disparities in both age-standardised burden rate and changing trend of anxiety disorders in sex, country and age. In 2019, 7.07% of the global DALYs due to anxiety disorders were attributable to bullying victimisation, mainly among the population aged 5–39 years, and the proportion increased in almost all countries and territories compared with 1990. CONCLUSION: Anxiety disorder is still the most common mental illness in the world and has a striking impact on the global burden of disease. Controlling potential risk factors, such as bullying, establishing effective mental health knowledge dissemination and diversifying intervention strategies adapted to specific characteristics will reduce the burden of anxiety disorders. Cambridge University Press 2021-05-06 /pmc/articles/PMC8157816/ /pubmed/33955350 http://dx.doi.org/10.1017/S2045796021000275 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0), which permits unrestricted re- use, distribution and reproduction, provided the original article is properly cited.
spellingShingle Original Article
Yang, Xiaorong
Fang, Yuan
Chen, Hui
Zhang, Tongchao
Yin, Xiaolin
Man, Jinyu
Yang, Lejin
Lu, Ming
Global, regional and national burden of anxiety disorders from 1990 to 2019: results from the Global Burden of Disease Study 2019
title Global, regional and national burden of anxiety disorders from 1990 to 2019: results from the Global Burden of Disease Study 2019
title_full Global, regional and national burden of anxiety disorders from 1990 to 2019: results from the Global Burden of Disease Study 2019
title_fullStr Global, regional and national burden of anxiety disorders from 1990 to 2019: results from the Global Burden of Disease Study 2019
title_full_unstemmed Global, regional and national burden of anxiety disorders from 1990 to 2019: results from the Global Burden of Disease Study 2019
title_short Global, regional and national burden of anxiety disorders from 1990 to 2019: results from the Global Burden of Disease Study 2019
title_sort global, regional and national burden of anxiety disorders from 1990 to 2019: results from the global burden of disease study 2019
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157816/
https://www.ncbi.nlm.nih.gov/pubmed/33955350
http://dx.doi.org/10.1017/S2045796021000275
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