Cargando…

Generation of Non-Small Cell Lung Cancer Patient-Derived Xenografts to Study Intratumor Heterogeneity

SIMPLE SUMMARY: It is widely thought that tumors are composed of different subpopulations of cancer cells carrying genetic alterations with some of them being common among all cells while others are unique for each subpopulation. This variable genetic profile of tumor cells is a component of what is...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kanaki, Zoi, Voutsina, Alexandra, Markou, Athina, Pateras, Ioannis S., Potaris, Konstantinos, Avgeris, Margaritis, Makrythanasis, Periklis, Athanasiadis, Emmanouil I., Vamvakaris, Ioannis, Patsea, Eleni, Vachlas, Konstantinos, Lianidou, Evi, Georgoulias, Vassilis, Kotsakis, Athanasios, Klinakis, Apostolos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157865/ https://www.ncbi.nlm.nih.gov/pubmed/34070013 http://dx.doi.org/10.3390/cancers13102446

Ejemplares similares

Preoperative Mutational Analysis of Circulating Tumor Cells (CTCs) and Plasma-cfDNA Provides Complementary Information for Early Prediction of Relapse: A Pilot Study in Early-Stage Non-Small Cell Lung Cancer
por: Markou, A. N., et al.
Publicado: (2023)

Clinical Activity of an hTERT-Specific Cancer Vaccine (Vx-001) in “Immune Desert” NSCLC
por: Pateras, Ioannis S., et al.
Publicado: (2021)

DNA methylation analysis of tumor suppressor genes in liquid biopsy components of early stage NSCLC: a promising tool for early detection
por: Markou, Α., et al.
Publicado: (2022)

Detection of EGFR Mutations in Plasma cfDNA and Paired CTCs of NSCLC Patients before and after Osimertinib Therapy Using Crystal Digital PCR
por: Ntzifa, Aliki, et al.
Publicado: (2021)

HPV16 E6/E7 expression in circulating tumor cells in oropharyngeal squamous cell cancers: A pilot study
por: Economopoulou, Panagiota, et al.
Publicado: (2019)

KMT2C promoter methylation in plasma‐circulating tumor DNA is a prognostic biomarker in non‐small cell lung cancer
por: Mastoraki, Sofia, et al.
Publicado: (2020)

DNA Methylation Analysis in Plasma Cell-Free DNA and Paired CTCs of NSCLC Patients before and after Osimertinib Treatment
por: Ntzifa, Aliki, et al.
Publicado: (2021)

Gene expression in circulating tumor cells reveals a dynamic role of EMT and PD-L1 during osimertinib treatment in NSCLC patients
por: Ntzifa, Aliki, et al.
Publicado: (2021)

ESR1 NAPA Assay: Development and Analytical Validation of a Highly Sensitive and Specific Blood-Based Assay for the Detection of ESR1 Mutations in Liquid Biopsies
por: Stergiopoulou, Dimitra, et al.
Publicado: (2021)

The lysine‐specific methyltransferase KMT2C/MLL3 regulates DNA repair components in cancer
por: Rampias, Theodoros, et al.
Publicado: (2019)

PD-L1/pS6 in Circulating Tumor Cells (CTCs) during Osimertinib Treatment in Patients with Non-Small Cell Lung Cancer (NSCLC)
por: Pantazaka, Evangelia, et al.
Publicado: (2022)

Lung tumor MHCII immunity depends on in situ antigen presentation by fibroblasts
por: Kerdidani, Dimitra, et al.
Publicado: (2022)

Prognostic Significance of TWIST1, CD24, CD44, and ALDH1 Transcript Quantification in EpCAM-Positive Circulating Tumor Cells from Early Stage Breast Cancer Patients
por: Strati, Areti, et al.
Publicado: (2019)

RNA-Based CTC Analysis Provides Prognostic Information in Metastatic Breast Cancer
por: Strati, Areti, et al.
Publicado: (2021)

PIK3CA hotspot mutations in circulating tumor cells and paired circulating tumor DNA in breast cancer: a direct comparison study
por: Tzanikou, Eleni, et al.
Publicado: (2019)

Effect of Osimertinib on CTCs and ctDNA in EGFR Mutant Non-Small Cell Lung Cancer Patients: The Prognostic Relevance of Liquid Biopsy
por: Kallergi, Galatea, et al.
Publicado: (2022)

Small Extracellular Vesicles in Pre-Therapy Plasma Predict Clinical Outcome in Non-Small-Cell Lung Cancer Patients
por: Vetsika, Eleni-Kyriaki, et al.
Publicado: (2021)

Evaluation of Monocarboxylate Transporter 4 (MCT4) Expression and Its Prognostic Significance in Circulating Tumor Cells From Patients With Early Stage Non-Small-Cell Lung Cancer
por: Markou, Athina, et al.
Publicado: (2021)

Comprehensive liquid biopsy analysis as a tool for the early detection of minimal residual disease in breast cancer
por: Stergiopoulou, Dimitra, et al.
Publicado: (2023)

Metabolism-Related Gene Expression in Circulating Tumor Cells from Patients with Early Stage Non-Small Cell Lung Cancer
por: Zafeiriadou, A., et al.
Publicado: (2022)

Direct comparison study of DNA methylation markers in EpCAM-positive circulating tumour cells, corresponding circulating tumour DNA, and paired primary tumours in breast cancer
por: Chimonidou, Maria, et al.
Publicado: (2017)

Loss of Kmt2c in vivo leads to EMT, mitochondrial dysfunction and improved response to lapatinib in breast cancer
por: Simigdala, Nikiana, et al.
Publicado: (2023)

Role of circulating free DNA in colorectal cancer
por: Matikas, Alexios, et al.
Publicado: (2016)

Gene expression profile of circulating tumor cells in breast cancer by RT-qPCR
por: Strati, Areti, et al.
Publicado: (2011)

Dll1 Marks Cells of Origin of Ras-Induced Cancer in Mouse Squamous Epithelia
por: Vasilaki, Eleni, et al.
Publicado: (2018)

Analytical methodologies for the detection of SARS-CoV-2 in wastewater: Protocols and future perspectives
por: Alygizakis, Nikiforos, et al.
Publicado: (2021)

How Do Cytokines Trigger Genomic Instability?
por: Aivaliotis, Ioannis L., et al.
Publicado: (2012)

Panitumumab in combination with modified docetaxel/cisplatin/5-fluorouracil as first-line treatment in gastric and gastroesophageal junction adenocarcinomas: a multicenter phase II study by the Hellenic Oncology Research Group
por: Kentepozidis, Nikolaos, et al.
Publicado: (2018)

A closed-tube methylation-sensitive high resolution melting assay (MS-HRMA) for the semi-quantitative determination of CST6 promoter methylation in clinical samples
por: Dimitrakopoulos, Lampros, et al.
Publicado: (2012)

Primary Mediastinal Neuroendocrine Tumor: A Case of Atypical Carcinoid
por: Kosmas, Konstantinos, et al.
Publicado: (2021)

Primary Gastric Malignant Melanoma
por: Kosmas, Konstantinos, et al.
Publicado: (2020)

Cell cyclins: triggering elements of cancer or not?
por: Stamatakos, Michael, et al.
Publicado: (2010)

Direct comparison of size-dependent versus EpCAM-dependent CTC enrichment at the gene expression and DNA methylation level in head and neck squamous cell carcinoma
por: Zavridou, Martha, et al.
Publicado: (2020)

KRT14 marks a subpopulation of bladder basal cells with pivotal role in regeneration and tumorigenesis
por: Papafotiou, George, et al.
Publicado: (2016)

miRNA-21 as a novel therapeutic target in lung cancer
por: Markou, Athina, et al.
Publicado: (2016)

Delta SARS-CoV-2 variant is entirely substituted by the omicron variant during the fifth COVID-19 wave in Attica region
por: Galani, Aikaterini, et al.
Publicado: (2023)

Corrigendum to “Delta SARS-CoV-2 variant is entirely substituted by the omicron variant during the fifth COVID-19 wave in Attica region” [Sci. Total Environ., 856(Pt 1) (2023)/159062]
por: Galani, Aikaterini, et al.
Publicado: (2023)

Hypoxia-inducible factor-1α and vascular endothelial growth factor expression in circulating tumor cells of breast cancer patients
por: Kallergi, Galatea, et al.
Publicado: (2009)

MiR-signing gastrointestinal (con-)tract cancer
por: Gorgoulis, Vassilis G., et al.
Publicado: (2017)

Evaluation of the Small Heat Shock Protein Family Members HSPB2 and HSPB3 in Bladder Cancer Prognosis and Progression
por: Gianniou, Despoina D., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_5u72ggpojagq79v245knuicl4l