Synthesis, Anticancer Screening of Some Novel Trimethoxy Quinazolines and VEGFR2, EGFR Tyrosine Kinase Inhibitors Assay; Molecular Docking Studies

A new series of 8-methoxy-2-trimethoxyphenyl-3-substituted quinazoline-4(3)-one compounds were designed, synthesized, and screened for antitumor activity against three cell lines, namely, Hela, A549, and MDA compared to docetaxel as reference drug. The molecular docking was performed using Autodock...

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Detalles Bibliográficos
Autores principales: Altamimi, Abdulmalik S., El-Azab, Adel S., Abdelhamid, Sami G., Alamri, Mubarak A., Bayoumi, Ashraf H., Alqahtani, Safar M., Alabbas, Alhumaidi B., Altharawi, Ali I., Alossaimi, Manal A., Mohamed, Menshawy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157871/
https://www.ncbi.nlm.nih.gov/pubmed/34069962
http://dx.doi.org/10.3390/molecules26102992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157871/
https://www.ncbi.nlm.nih.gov/pubmed/34069962
http://dx.doi.org/10.3390/molecules26102992

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