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Synthesis, Anticancer Screening of Some Novel Trimethoxy Quinazolines and VEGFR2, EGFR Tyrosine Kinase Inhibitors Assay; Molecular Docking Studies
A new series of 8-methoxy-2-trimethoxyphenyl-3-substituted quinazoline-4(3)-one compounds were designed, synthesized, and screened for antitumor activity against three cell lines, namely, Hela, A549, and MDA compared to docetaxel as reference drug. The molecular docking was performed using Autodock...
Autores principales: | Altamimi, Abdulmalik S., El-Azab, Adel S., Abdelhamid, Sami G., Alamri, Mubarak A., Bayoumi, Ashraf H., Alqahtani, Safar M., Alabbas, Alhumaidi B., Altharawi, Ali I., Alossaimi, Manal A., Mohamed, Menshawy A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157871/ https://www.ncbi.nlm.nih.gov/pubmed/34069962 http://dx.doi.org/10.3390/molecules26102992 |
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