Cargando…
Physiological concentrations of cyanide stimulate mitochondrial Complex IV and enhance cellular bioenergetics
In mammalian cells, cyanide is viewed as a cytotoxic agent, which exerts its effects through inhibition of mitochondrial Complex IV (Cytochrome C oxidase [CCOx]). However, the current report demonstrates that cyanide’s effect on CCOx is biphasic; low (nanomolar to low-micromolar) concentrations stim...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157914/ https://www.ncbi.nlm.nih.gov/pubmed/33972444 http://dx.doi.org/10.1073/pnas.2026245118 |