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TSG101 negatively regulates mitochondrial biogenesis in axons

There is a tight association between mitochondrial dysfunction and neurodegenerative diseases and axons that are particularly vulnerable to degeneration, but how mitochondria are maintained in axons to support their physiology remains poorly defined. In an in vivo forward genetic screen for mutants...

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Detalles Bibliográficos
Autores principales:	Lin, Tzu-Huai, Bis-Brewer, Dana M., Sheehan, Amy E., Townsend, Louise N., Maddison, Daniel C., Züchner, Stephan, Smith, Gaynor A., Freeman, Marc R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2021
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157921/ https://www.ncbi.nlm.nih.gov/pubmed/33972422 http://dx.doi.org/10.1073/pnas.2018770118

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