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Single-cell sequencing reveals suppressive transcriptional programs regulated by MIS/AMH in neonatal ovaries
Müllerian inhibiting substance (MIS/AMH), produced by granulosa cells of growing follicles, is an important regulator of folliculogenesis and follicle development. Treatment with exogenous MIS in mice suppresses follicle development and prevents ovulation. To investigate the mechanisms by which MIS...
Autores principales: | Meinsohn, Marie-Charlotte, Saatcioglu, Hatice D., Wei, Lina, Li, Yi, Horn, Heiko, Chauvin, Maeva, Kano, Motohiro, Nguyen, Ngoc Minh Phuong, Nagykery, Nicholas, Kashiwagi, Aki, Samore, Wesley R., Wang, Dan, Oliva, Esther, Gao, Guangping, Morris, Mary E., Donahoe, Patricia K., Pépin, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157966/ https://www.ncbi.nlm.nih.gov/pubmed/33980714 http://dx.doi.org/10.1073/pnas.2100920118 |
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