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Adult Patient Preferences for Long-Acting ADHD Treatments: A Discrete Choice Experiment

BACKGROUND AND OBJECTIVE: Treatment for attention deficit hyperactivity disorder (ADHD) requires a multifaceted approach including psychosocial interventions and pharmacological treatment. This study evaluates preferences for specific attributes associated with different long-acting stimulant treatm...

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Autores principales: Cambron-Mellott, M Janelle, Mikl, Jaromir, Matos, Joana E, Erensen, Jennifer G, Beusterien, Kathleen, Cataldo, Marc J, Hallissey, Bernadette, Mattingly, Gregory W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158042/
https://www.ncbi.nlm.nih.gov/pubmed/34054292
http://dx.doi.org/10.2147/PPA.S311836
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author Cambron-Mellott, M Janelle
Mikl, Jaromir
Matos, Joana E
Erensen, Jennifer G
Beusterien, Kathleen
Cataldo, Marc J
Hallissey, Bernadette
Mattingly, Gregory W
author_facet Cambron-Mellott, M Janelle
Mikl, Jaromir
Matos, Joana E
Erensen, Jennifer G
Beusterien, Kathleen
Cataldo, Marc J
Hallissey, Bernadette
Mattingly, Gregory W
author_sort Cambron-Mellott, M Janelle
collection PubMed
description BACKGROUND AND OBJECTIVE: Treatment for attention deficit hyperactivity disorder (ADHD) requires a multifaceted approach including psychosocial interventions and pharmacological treatment. This study evaluates preferences for specific attributes associated with different long-acting stimulant treatment among US adults with ADHD. METHODS: Patients completed an online, cross-sectional survey, incorporating a discrete choice experiment to assess preferences for attributes. RESULTS: Analyses included 200 adults with ADHD (mean age 33.0 years; 60% self-reporting moderate severity); the mean (SD) Adult ADHD Self-Report Scale-v1.1 score was 45.9 (12.4). Overall, patients valued speed of onset most and risk of rebound least. Three population groups with distinct preferences were identified: side effect-driven (n=69, 35%), quick onset-driven (n=47, 24%) and quick onset and long duration-driven (n=84, 42%). CONCLUSION: This study shows differences in how adults with ADHD value and assess benefit-risk trade-offs when considering the desired attributes of stimulant treatments, highlighting the importance of patient-physician shared decision-making to optimize the desired benefits of individualized treatment.
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spelling pubmed-81580422021-05-28 Adult Patient Preferences for Long-Acting ADHD Treatments: A Discrete Choice Experiment Cambron-Mellott, M Janelle Mikl, Jaromir Matos, Joana E Erensen, Jennifer G Beusterien, Kathleen Cataldo, Marc J Hallissey, Bernadette Mattingly, Gregory W Patient Prefer Adherence Original Research BACKGROUND AND OBJECTIVE: Treatment for attention deficit hyperactivity disorder (ADHD) requires a multifaceted approach including psychosocial interventions and pharmacological treatment. This study evaluates preferences for specific attributes associated with different long-acting stimulant treatment among US adults with ADHD. METHODS: Patients completed an online, cross-sectional survey, incorporating a discrete choice experiment to assess preferences for attributes. RESULTS: Analyses included 200 adults with ADHD (mean age 33.0 years; 60% self-reporting moderate severity); the mean (SD) Adult ADHD Self-Report Scale-v1.1 score was 45.9 (12.4). Overall, patients valued speed of onset most and risk of rebound least. Three population groups with distinct preferences were identified: side effect-driven (n=69, 35%), quick onset-driven (n=47, 24%) and quick onset and long duration-driven (n=84, 42%). CONCLUSION: This study shows differences in how adults with ADHD value and assess benefit-risk trade-offs when considering the desired attributes of stimulant treatments, highlighting the importance of patient-physician shared decision-making to optimize the desired benefits of individualized treatment. Dove 2021-05-21 /pmc/articles/PMC8158042/ /pubmed/34054292 http://dx.doi.org/10.2147/PPA.S311836 Text en © 2021 Cambron-Mellott et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Cambron-Mellott, M Janelle
Mikl, Jaromir
Matos, Joana E
Erensen, Jennifer G
Beusterien, Kathleen
Cataldo, Marc J
Hallissey, Bernadette
Mattingly, Gregory W
Adult Patient Preferences for Long-Acting ADHD Treatments: A Discrete Choice Experiment
title Adult Patient Preferences for Long-Acting ADHD Treatments: A Discrete Choice Experiment
title_full Adult Patient Preferences for Long-Acting ADHD Treatments: A Discrete Choice Experiment
title_fullStr Adult Patient Preferences for Long-Acting ADHD Treatments: A Discrete Choice Experiment
title_full_unstemmed Adult Patient Preferences for Long-Acting ADHD Treatments: A Discrete Choice Experiment
title_short Adult Patient Preferences for Long-Acting ADHD Treatments: A Discrete Choice Experiment
title_sort adult patient preferences for long-acting adhd treatments: a discrete choice experiment
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158042/
https://www.ncbi.nlm.nih.gov/pubmed/34054292
http://dx.doi.org/10.2147/PPA.S311836
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