Development of Pelubiprofen Tromethamine with Improved Gastrointestinal Safety and Absorption

Pelubiprofen (PEL), which is a commercialized non-steroidal anti-inflammatory drug (NSAID), is associated with the risk of gastrointestinal (GI) adverse events following long-term exposure and has poor water-soluble properties. Here, a new pelubiprofen tromethamine (PEL-T) with improved solubility,...

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Detalles Bibliográficos
Autores principales: Park, Ji Yeon, Oh, Dong Ho, Park, Sang-Wook, Chae, Bo Ram, Kim, Chul Woo, Han, Sang Heon, Shin, Hyeon Jong, Yeom, Soo Bin, Lee, Da Yeong, Park, Min Kyu, Park, Sang-Eun, Park, Jun-Bom, Lee, Kyung-Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158122/
https://www.ncbi.nlm.nih.gov/pubmed/34070062
http://dx.doi.org/10.3390/pharmaceutics13050745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158122/
https://www.ncbi.nlm.nih.gov/pubmed/34070062
http://dx.doi.org/10.3390/pharmaceutics13050745

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