Lysosome activable polymeric vorinostat encapsulating PD-L1KD for a combination of HDACi and immunotherapy

PD-1/PD-L1 blocking therapy has become one of the most promising methods in the field of tumor treatment. However, it encounters the challenge of immune escape due to the exhaustion of T cells. Studies have shown that the epigenetic regulation drug histone deacetylase inhibitor (HDACi) may be able t...

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Detalles Bibliográficos
Autores principales: Lu, Fengkun, Hou, Lei, Wang, Sizhen, Yu, Yingjie, Zhang, Yunchang, Sun, Linhong, Wang, Chen, Ma, Zhiqiang, Yang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158275/
https://www.ncbi.nlm.nih.gov/pubmed/34036867
http://dx.doi.org/10.1080/10717544.2021.1927246

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