Cargando…
Obesity in Humans Is Characterized by Gut Inflammation as Shown by Pro-Inflammatory Intestinal Macrophage Accumulation
Chronic low-grade inflammation is a hallmark of obesity and associated with cardiovascular complications. However, it remains unclear where this inflammation starts. As the gut is constantly exposed to food, gut microbiota, and metabolites, we hypothesized that mucosal immunity triggers an innate in...
Autores principales: | Rohm, Theresa V., Fuchs, Regula, Müller, Rahel L., Keller, Lena, Baumann, Zora, Bosch, Angela J. T., Schneider, Romano, Labes, Danny, Langer, Igor, Pilz, Julia B., Niess, Jan H., Delko, Tarik, Hruz, Petr, Cavelti-Weder, Claudia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158297/ https://www.ncbi.nlm.nih.gov/pubmed/34054838 http://dx.doi.org/10.3389/fimmu.2021.668654 |
Ejemplares similares
-
Lung versus gut exposure to air pollution particles differentially affect metabolic health in mice
por: Bosch, Angela J. T., et al.
Publicado: (2023) -
Diesel Exhaust Particle (DEP)-induced glucose intolerance is driven by an intestinal innate immune response and NLRP3 activation in mice
por: Bosch, Angela J. T., et al.
Publicado: (2023) -
Targeting colonic macrophages improves glycemic control in high-fat diet-induced obesity
por: Rohm, Theresa V., et al.
Publicado: (2022) -
Imatinib reduces non-alcoholic fatty liver disease in obese mice by targeting inflammatory and lipogenic pathways in macrophages and liver
por: AlAsfoor, Shefaa, et al.
Publicado: (2018) -
CSF1R inhibition with PLX5622 affects multiple immune cell compartments and induces tissue-specific metabolic effects in lean mice
por: Bosch, Angela J. T., et al.
Publicado: (2023)