Cargando…

Rapamycin Modulates the Proinflammatory Memory-Like Response of Microglia Induced by BAFF

BACKGROUND: Recently trained immunity of microglia provided an opportunity to study the chronic effect of microglial activation and its metabolic rewiring in neuroimmunological diseases. Since elevated levels of B cell-activating factor (BAFF) have been proved to be associated with some chronic neur...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Jianing, Yang, Chunshu, Hou, Xiaoyu, Xu, Jingyi, Yun, Yang, Qin, Ling, Yang, Pingting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158300/ https://www.ncbi.nlm.nih.gov/pubmed/34054807 http://dx.doi.org/10.3389/fimmu.2021.639049

Ejemplares similares

Lupus serum IgG induces microglia activation through Fc fragment dependent way and modulated by B-cell activating factor
por: Yang, Chunshu, et al.
Publicado: (2019)

Disturbance of neuron–microglia crosstalk mediated by GRP78 in Neuropsychiatric systemic lupus erythematosus mice
por: Xu, Jingyi, et al.
Publicado: (2023)

BAFF and BAFF-Receptor in B Cell Selection and Survival
por: Smulski, Cristian R., et al.
Publicado: (2018)

Inhibition of Membrane-Bound BAFF by the Anti-BAFF Antibody Belimumab
por: Kowalczyk-Quintas, Christine, et al.
Publicado: (2018)

The Interplay of IL-21 and BAFF in the Formation and Maintenance of Human B Cell Memory
por: Karnell, Jodi L., et al.
Publicado: (2012)

Modifications of the BAFF/BAFF-Receptor Axis in Patients With Pemphigus Treated With Rituximab Versus Standard Corticosteroid Regimen
por: Hébert, Vivien, et al.
Publicado: (2021)

Rapamycin prevents the impairments of social recognition induced by anti-P antibody in a murine model
por: Wang, Xuejiao, et al.
Publicado: (2020)

CMTM6: increased circulating level and up-regulated expression in labial salivary glands in patients with primary Sjogren’s syndrome
por: Qian, Sirui, et al.
Publicado: (2021)

Memory-Like Responses of Brain Microglia Are Controlled by Developmental State and Pathogen Dose
por: Lajqi, Trim, et al.
Publicado: (2020)

BAFF system expression in double negative 2, activated naïve and activated memory B cells in systemic lupus erythematosus
por: Álvarez Gómez, Jhonatan Antonio, et al.
Publicado: (2023)

Elevated BAFF Levels in the Cerebrospinal Fluid of Patients with Neuro-Behçet's Disease: BAFF is Correlated with Progressive Dementia and Psychosis
por: Sumita, Y, et al.
Publicado: (2012)

TREM1 Regulates Neuroinflammatory Injury by Modulate Proinflammatory Subtype Transition of Microglia and Formation of Neutrophil Extracellular Traps via Interaction With SYK in Experimental Subarachnoid Hemorrhage
por: Wu, Xinyan, et al.
Publicado: (2021)

Treatment-Induced BAFF Expression and B Cell Biology in Multiple Sclerosis
por: Smets, Ide, et al.
Publicado: (2021)

Nutritional and Nanotechnological Modulators of Microglia
por: Maysinger, Dusica, et al.
Publicado: (2016)

Memory-Like Inflammatory Responses of Microglia to Rising Doses of LPS: Key Role of PI3Kγ
por: Lajqi, Trim, et al.
Publicado: (2019)

Proinflammatory Microenvironment During Kingella kingae Infection Modulates Osteoclastogenesis
por: Pesce Viglietti, Ayelén Ivana, et al.
Publicado: (2021)

Neuroprotective effect of microglia against impairments of auditory steady-state response induced by anti-P IgG from SLE patients in naïve mice
por: Wang, Xuejiao, et al.
Publicado: (2020)

Genetic Variants of the BAFF Gene and Risk of Fatigue Among Patients With Primary Sjögren’s Syndrome
por: Flessa, Christina-Maria, et al.
Publicado: (2022)

Natural Killer-Like B Cells Secreting Interleukin-18 Induces a Proinflammatory Response in Periodontitis
por: Zhang, Ye, et al.
Publicado: (2021)

New Insights for RANKL as a Proinflammatory Modulator in Modeled Inflammatory Arthritis
por: Papadaki, Maria, et al.
Publicado: (2019)

Molecular Mechanisms Modulating the Phenotype of Macrophages and Microglia
por: Amici, Stephanie A., et al.
Publicado: (2017)

BAFF Attenuates Immunosuppressive Monocytes in the Melanoma Tumor Microenvironment
por: Liu, Wei, et al.
Publicado: (2022)

Evolutionarily Selected Overexpression of the Cytokine BAFF Enhances Mucosal Immune Response Against P. falciparum
por: Lodde, Valeria, et al.
Publicado: (2020)

BAFF Blockade Attenuates Inflammatory Responses and Intestinal Barrier Dysfunction in a Murine Endotoxemia Model
por: Quan, Runze, et al.
Publicado: (2020)

B cell-activating factor (BAFF) from dendritic cells, monocytes and neutrophils is required for B cell maturation and autoantibody production in SLE-like autoimmune disease
por: Giordano, Daniela, et al.
Publicado: (2023)

Bacterial Lipoproteins Induce BAFF Production via TLR2/MyD88/JNK Signaling Pathways in Dendritic Cells
por: Im, Jintaek, et al.
Publicado: (2020)

Data for the crystal structure of APRIL–BAFF–BAFF heterotrimer
por: Maskos, Klaus, et al.
Publicado: (2015)

Pristane induced lupus mice as a model for neuropsychiatric lupus (NPSLE)
por: Yun, Yang, et al.
Publicado: (2023)

Circulating Memory B Cells in Early Multiple Sclerosis Exhibit Increased IgA(+) Cells, Globally Decreased BAFF-R Expression and an EBV-Related IgM(+) Cell Signature
por: Leffler, Jonatan, et al.
Publicado: (2022)

(1)IFN-α Modulates Memory Tfh Cells and Memory B Cells in Mice, Following Recombinant FMDV Adenoviral Challenge
por: Duan, Xiangguo, et al.
Publicado: (2020)

Central role of microglia in sepsis-associated encephalopathy: From mechanism to therapy
por: Yan, Xiaoqian, et al.
Publicado: (2022)

BAFF Controls Neural Cell Survival through BAFF Receptor
por: Tada, Satoru, et al.
Publicado: (2013)

Non-Canonical NF-κB Signaling Initiated by BAFF Influences B Cell Biology at Multiple Junctures
por: Gardam, Sandra, et al.
Publicado: (2014)

Impact of BAFF Blockade on Inflammation, Germinal Center Reaction and Effector B-Cells During Acute SIV Infection
por: Borhis, Gwenoline, et al.
Publicado: (2020)

Analysis of lncRNA and mRNA Repertoires in Lung From BAFF-R-Deficient Pneumocystis-Infected Mice
por: Rong, Heng-Mo, et al.
Publicado: (2022)

Inhibition of Notch1 Signaling Alleviates Endotoxin-Induced Inflammation Through Modulating Retinal Microglia Polarization
por: Cheng, Zhixing, et al.
Publicado: (2019)

Approaching Inflammation Paradoxes—Proinflammatory Cytokine Blockages Induce Inflammatory Regulators
por: Liu, Ming, et al.
Publicado: (2020)

BAFF blockade attenuates acute graft-versus-host disease directly via the dual regulation of T- and B-cell homeostasis
por: Jeon, Youngwoo, et al.
Publicado: (2022)

Interaction of Microglia and Astrocytes in the Neurovascular Unit
por: Liu, Li-rong, et al.
Publicado: (2020)

Critical requirement for BCR, BAFF, and BAFFR in memory B cell survival
por: Müller-Winkler, Jennifer, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_0d7utaj6rim3vblh295i5pl00j