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CX3CL1 Overexpression Prevents the Formation of Lung Metastases in Trastuzumab-Treated MDA-MB-453-Based Humanized Tumor Mice (HTM)

SIMPLE SUMMARY: In about 15–18% of breast cancers the HER2 gene is amplified, which allows an anti-HER2 treatment. However, about 50% of HER2-positive patients experience de novo or acquired resistance to the antibody-based therapy with trastuzumab. Therefore, the identification of predictive marker...

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Detalles Bibliográficos
Autores principales:	Wege, Anja Kathrin, Dreyer, Tobias F., Teoman, Attila, Ortmann, Olaf, Brockhoff, Gero, Bronger, Holger
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158361/ https://www.ncbi.nlm.nih.gov/pubmed/34070094 http://dx.doi.org/10.3390/cancers13102459

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