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4-Fluoro-Threonine: From Diastereoselective Synthesis to pH-Dependent Conformational Equilibrium in Aqueous Solution

[Image: see text] 4-Fluoro-threonine, the only fluoro amino acid of natural origin discovered so far, is an interesting target for both synthetic and theoretical investigations. In this work, we lay the foundation for spectroscopic characterization of 4-fluoro-threonine. First, we report a diastereo...

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Detalles Bibliográficos
Autores principales: Potenti, Simone, Spada, Lorenzo, Fusè, Marco, Mancini, Giordano, Gualandi, Andrea, Leonardi, Costanza, Cozzi, Pier Giorgio, Puzzarini, Cristina, Barone, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158790/
https://www.ncbi.nlm.nih.gov/pubmed/34056467
http://dx.doi.org/10.1021/acsomega.1c01007