Cargando…

Novel Descriptors Derived from the Aggregation Propensity of Di- and Tripeptides Can Predict the Critical Aggregation Concentration of Longer Peptides

[Image: see text] Self-assembling amphiphilic peptides have recently received special attention in medicine. Nonetheless, testing the myriad of combinations generated from at least 20 coded and several hundreds of noncoded amino acids to obtain candidate sequences for each application, if possible,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zanganeh, Saeed, Firoozpour, Loghman, Sardari, Soroush, Afgar, Ali, Cohan, Reza Ahangari, Mohajel, Nasir
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158804/ https://www.ncbi.nlm.nih.gov/pubmed/34056481 http://dx.doi.org/10.1021/acsomega.1c01293

Ejemplares similares

Structure Based Descriptors for the Estimation of Colloidal Interactions and Protein Aggregation Propensities
por: Brunsteiner, Michael, et al.
Publicado: (2013)

N-Substituted indole carbohydrazide derivatives: synthesis and evaluation of their antiplatelet aggregation activity
por: Mirfazli, Seyedeh Sara, et al.
Publicado: (2014)

Aggregation Propensity of the Human Proteome
por: Monsellier, Elodie, et al.
Publicado: (2008)

Predicting the aggregation number of cationic surfactants based on ANN-QSAR modeling approaches: understanding the impact of molecular descriptors on aggregation numbers
por: Abdous, Behnaz, et al.
Publicado: (2022)

Tau Aggregation Propensity Engrained in Its Solution State
por: Eschmann, Neil A., et al.
Publicado: (2015)

Molecular dynamics analysis of the aggregation propensity of polyglutamine segments
por: Wen, Jingran, et al.
Publicado: (2017)

Is Desmin Propensity to Aggregate Part of its Protective Function?
por: Singh, Sonia R., et al.
Publicado: (2020)

Spreading of Tau Protein Does Not Depend on Aggregation Propensity
por: Rodrigues, Sara, et al.
Publicado: (2023)

Bioactive and Sensory Di- and Tripeptides Generated during Dry-Curing of Pork Meat
por: Heres, Alejandro, et al.
Publicado: (2023)

The Threat of Instability: Neurodegeneration Predicted by Protein Destabilization and Aggregation Propensity
por: Meiering, Elizabeth M
Publicado: (2008)

Aggregation propensity of neuronal receptors: potential implications in neurodegenerative disorders
por: Navarro, Susanna, et al.
Publicado: (2015)

An acetylation–phosphorylation switch that regulates tau aggregation propensity and function
por: Carlomagno, Yari, et al.
Publicado: (2017)

The strong propensity of Cadherin‐23 for aggregation inhibits cell migration
por: Sannigrahi, Malay K., et al.
Publicado: (2019)

SODA: prediction of protein solubility from disorder and aggregation propensity
por: Paladin, Lisanna, et al.
Publicado: (2017)

Susceptibility of Mutant SOD1 to Form a Destabilized Monomer Predicts Cellular Aggregation and Toxicity but Not In vitro Aggregation Propensity
por: McAlary, Luke, et al.
Publicado: (2016)

Synthesis of New 3-Arylcoumarins Bearing N-Benzyl Triazole Moiety: Dual Lipoxygenase and Butyrylcholinesterase Inhibitors With Anti-Amyloid Aggregation and Neuroprotective Properties Against Alzheimer’s Disease
por: Pourabdi, Ladan, et al.
Publicado: (2022)

Improvement of Certolizumab Fab′ properties by PASylation technology
por: Mazaheri, Somayeh, et al.
Publicado: (2020)

Prion protein insertional mutations increase aggregation propensity but not fiber stability
por: Kalastavadi, Tejas, et al.
Publicado: (2008)

Phosphorylation as a Tool To Modulate Aggregation Propensity and To Predict Fibril Architecture
por: Valette, Nathalie M, et al.
Publicado: (2012)

The degradation pathway of a model misfolded protein is determined by aggregation propensity
por: Sun, Zhihao, et al.
Publicado: (2018)

AMYCO: evaluation of mutational impact on prion-like proteins aggregation propensity
por: Iglesias, Valentin, et al.
Publicado: (2019)

Propensity score stratification using bootstrap aggregating classification trees analysis
por: Otok, Bambang Widjanarko, et al.
Publicado: (2020)

N-alpha-acetylation of Huntingtin protein increases its propensity to aggregate
por: Gottlieb, Leah, et al.
Publicado: (2021)

Vehicle Detection in Aerial Images Using a Fast Oriented Region Search and the Vector of Locally Aggregated Descriptors
por: Liu, Chongyang, et al.
Publicado: (2019)

An Evolutionary Trade-Off between Protein Turnover Rate and Protein Aggregation Favors a Higher Aggregation Propensity in Fast Degrading Proteins
por: De Baets, Greet, et al.
Publicado: (2011)

Cryo-EM Structure of an Atypical Proton-Coupled Peptide Transporter: Di- and Tripeptide Permease C
por: Killer, Maxime, et al.
Publicado: (2022)

The Effects of Ca(2+) Concentration and E200K Mutation on the Aggregation Propensity of PrP(C): A Computational Study
por: Marrone, Alessandro, et al.
Publicado: (2016)

QSAR Study on Antioxidant Tripeptides and the Antioxidant Activity of the Designed Tripeptides in Free Radical Systems
por: Chen, Nan, et al.
Publicado: (2018)

Di‐ and Tetracyano‐Substituted Pyrene‐Fused Pyrazaacenes: Aggregation in the Solid State
por: Ueberricke, Lucas, et al.
Publicado: (2020)

Semisynthetic Modification of Tau Protein with Di-Ubiquitin Chains for Aggregation Studies
por: Munari, Francesca, et al.
Publicado: (2020)

Requirement of aggregation propensity of Alzheimer amyloid peptides for neuronal cell surface binding
por: Bateman, David A, et al.
Publicado: (2007)

Structural coalescence underlies the aggregation propensity of a β-barrel protein motif
por: Angelani, Carla R., et al.
Publicado: (2017)

The Effects of Lipid Membranes, Crowding and Osmolytes on the Aggregation, and Fibrillation Propensity of Human IAPP
por: Gao, Mimi, et al.
Publicado: (2015)

Tau local structure shields an amyloid-forming motif and controls aggregation propensity
por: Chen, Dailu, et al.
Publicado: (2019)

Ionic Liquid-Based Strategy for Predicting Protein Aggregation Propensity and Thermodynamic Stability
por: Shmool, Talia A., et al.
Publicado: (2022)

A3DyDB: exploring structural aggregation propensities in the yeast proteome
por: Garcia-Pardo, Javier, et al.
Publicado: (2023)

Exploiting the aggregation propensity of beta-lactamases to design inhibitors that induce enzyme misfolding
por: Khodaparast, Ladan, et al.
Publicado: (2023)

Investigation of the effect of hydrochloric acid with different concentrations on mineral trioxide aggregate plug and dentin
por: Gharechahi, Maryam, et al.
Publicado: (2023)

Automatic detection and resolution of measurement-unit conflicts in aggregated data
por: Samadian, Soroush, et al.
Publicado: (2014)

To aggregate or not to aggregate high-dimensional classifiers
por: Xu, Cheng-Jian, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_mk3t51k72fatm2fh23t3m5gsge