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Aryl N-[ω-(6-Fluoroindol-1-yl)alkyl]carbamates as Inhibitors of Fatty Acid Amide Hydrolase, Monoacylglycerol Lipase, and Butyrylcholinesterase: Structure–Activity Relationships and Hydrolytic Stability

[Image: see text] A series of aryl N-[ω-(6-fluoroindol-1-yl)alkyl]carbamates with alkyl spacers of varying lengths between the indole and the carbamate group and with differently substituted aryl moieties at the carbamate oxygen were synthesized and tested for inhibition of the pharmacologically int...

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Detalles Bibliográficos
Autores principales: Rudolph, Stefan, Dahlhaus, Helmut, Hanekamp, Walburga, Albers, Christian, Barth, Maximilian, Michels, Giulia, Friedrich, Denise, Lehr, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158844/
https://www.ncbi.nlm.nih.gov/pubmed/34056494
http://dx.doi.org/10.1021/acsomega.1c01699

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