Cargando…

Estimating direct and spill-over impacts of political elections on COVID-19 transmission using synthetic control methods

Mass gathering events have been identified as high-risk environments for community transmission of coronavirus disease 2019 (COVID-19). Empirical estimates of their direct and spill-over effects however remain challenging to identify. In this study, we propose the use of a novel synthetic control fr...

Descripción completa

Detalles Bibliográficos
Autores principales: Lim, Jue Tao, Maung, Kenwin, Tan, Sok Teng, Ong, Suan Ee, Lim, Jane Mingjie, Koo, Joel Ruihan, Sun, Haoyang, Park, Minah, Tan, Ken Wei, Yoong, Joanne, Cook, Alex R., Dickens, Borame Sue Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158864/
https://www.ncbi.nlm.nih.gov/pubmed/34043622
http://dx.doi.org/10.1371/journal.pcbi.1008959
_version_ 1783699956143489024
author Lim, Jue Tao
Maung, Kenwin
Tan, Sok Teng
Ong, Suan Ee
Lim, Jane Mingjie
Koo, Joel Ruihan
Sun, Haoyang
Park, Minah
Tan, Ken Wei
Yoong, Joanne
Cook, Alex R.
Dickens, Borame Sue Lee
author_facet Lim, Jue Tao
Maung, Kenwin
Tan, Sok Teng
Ong, Suan Ee
Lim, Jane Mingjie
Koo, Joel Ruihan
Sun, Haoyang
Park, Minah
Tan, Ken Wei
Yoong, Joanne
Cook, Alex R.
Dickens, Borame Sue Lee
author_sort Lim, Jue Tao
collection PubMed
description Mass gathering events have been identified as high-risk environments for community transmission of coronavirus disease 2019 (COVID-19). Empirical estimates of their direct and spill-over effects however remain challenging to identify. In this study, we propose the use of a novel synthetic control framework to obtain causal estimates for direct and spill-over impacts of these events. The Sabah state elections in Malaysia were used as an example for our proposed methodology and we investigate the event’s spatial and temporal impacts on COVID-19 transmission. Results indicate an estimated (i) 70.0% of COVID-19 case counts within Sabah post-state election were attributable to the election’s direct effect; (ii) 64.4% of COVID-19 cases in the rest of Malaysia post-state election were attributable to the election’s spill-over effects. Sensitivity analysis was further conducted by examining epidemiological pre-trends, surveillance efforts, varying synthetic control matching characteristics and spill-over specifications. We demonstrate that our estimates are not due to pre-existing epidemiological trends, surveillance efforts, and/or preventive policies. These estimates highlight the potential of mass gatherings in one region to spill-over into an outbreak of national scale. Relaxations of mass gathering restrictions must therefore be carefully considered, even in the context of low community transmission and enforcement of safe distancing guidelines.
format Online
Article
Text
id pubmed-8158864
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-81588642021-06-09 Estimating direct and spill-over impacts of political elections on COVID-19 transmission using synthetic control methods Lim, Jue Tao Maung, Kenwin Tan, Sok Teng Ong, Suan Ee Lim, Jane Mingjie Koo, Joel Ruihan Sun, Haoyang Park, Minah Tan, Ken Wei Yoong, Joanne Cook, Alex R. Dickens, Borame Sue Lee PLoS Comput Biol Research Article Mass gathering events have been identified as high-risk environments for community transmission of coronavirus disease 2019 (COVID-19). Empirical estimates of their direct and spill-over effects however remain challenging to identify. In this study, we propose the use of a novel synthetic control framework to obtain causal estimates for direct and spill-over impacts of these events. The Sabah state elections in Malaysia were used as an example for our proposed methodology and we investigate the event’s spatial and temporal impacts on COVID-19 transmission. Results indicate an estimated (i) 70.0% of COVID-19 case counts within Sabah post-state election were attributable to the election’s direct effect; (ii) 64.4% of COVID-19 cases in the rest of Malaysia post-state election were attributable to the election’s spill-over effects. Sensitivity analysis was further conducted by examining epidemiological pre-trends, surveillance efforts, varying synthetic control matching characteristics and spill-over specifications. We demonstrate that our estimates are not due to pre-existing epidemiological trends, surveillance efforts, and/or preventive policies. These estimates highlight the potential of mass gatherings in one region to spill-over into an outbreak of national scale. Relaxations of mass gathering restrictions must therefore be carefully considered, even in the context of low community transmission and enforcement of safe distancing guidelines. Public Library of Science 2021-05-27 /pmc/articles/PMC8158864/ /pubmed/34043622 http://dx.doi.org/10.1371/journal.pcbi.1008959 Text en © 2021 Lim et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Lim, Jue Tao
Maung, Kenwin
Tan, Sok Teng
Ong, Suan Ee
Lim, Jane Mingjie
Koo, Joel Ruihan
Sun, Haoyang
Park, Minah
Tan, Ken Wei
Yoong, Joanne
Cook, Alex R.
Dickens, Borame Sue Lee
Estimating direct and spill-over impacts of political elections on COVID-19 transmission using synthetic control methods
title Estimating direct and spill-over impacts of political elections on COVID-19 transmission using synthetic control methods
title_full Estimating direct and spill-over impacts of political elections on COVID-19 transmission using synthetic control methods
title_fullStr Estimating direct and spill-over impacts of political elections on COVID-19 transmission using synthetic control methods
title_full_unstemmed Estimating direct and spill-over impacts of political elections on COVID-19 transmission using synthetic control methods
title_short Estimating direct and spill-over impacts of political elections on COVID-19 transmission using synthetic control methods
title_sort estimating direct and spill-over impacts of political elections on covid-19 transmission using synthetic control methods
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158864/
https://www.ncbi.nlm.nih.gov/pubmed/34043622
http://dx.doi.org/10.1371/journal.pcbi.1008959
work_keys_str_mv AT limjuetao estimatingdirectandspilloverimpactsofpoliticalelectionsoncovid19transmissionusingsyntheticcontrolmethods
AT maungkenwin estimatingdirectandspilloverimpactsofpoliticalelectionsoncovid19transmissionusingsyntheticcontrolmethods
AT tansokteng estimatingdirectandspilloverimpactsofpoliticalelectionsoncovid19transmissionusingsyntheticcontrolmethods
AT ongsuanee estimatingdirectandspilloverimpactsofpoliticalelectionsoncovid19transmissionusingsyntheticcontrolmethods
AT limjanemingjie estimatingdirectandspilloverimpactsofpoliticalelectionsoncovid19transmissionusingsyntheticcontrolmethods
AT koojoelruihan estimatingdirectandspilloverimpactsofpoliticalelectionsoncovid19transmissionusingsyntheticcontrolmethods
AT sunhaoyang estimatingdirectandspilloverimpactsofpoliticalelectionsoncovid19transmissionusingsyntheticcontrolmethods
AT parkminah estimatingdirectandspilloverimpactsofpoliticalelectionsoncovid19transmissionusingsyntheticcontrolmethods
AT tankenwei estimatingdirectandspilloverimpactsofpoliticalelectionsoncovid19transmissionusingsyntheticcontrolmethods
AT yoongjoanne estimatingdirectandspilloverimpactsofpoliticalelectionsoncovid19transmissionusingsyntheticcontrolmethods
AT cookalexr estimatingdirectandspilloverimpactsofpoliticalelectionsoncovid19transmissionusingsyntheticcontrolmethods
AT dickensboramesuelee estimatingdirectandspilloverimpactsofpoliticalelectionsoncovid19transmissionusingsyntheticcontrolmethods