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Resurgence of SARS-CoV-2: Detection by community viral surveillance

Surveillance of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has mainly relied on case reporting, which is biased by health service performance, test availability, and test-seeking behaviors. We report a community-wide national representative surveillance program in Engl...

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Autores principales: Riley, Steven, Ainslie, Kylie E. C., Eales, Oliver, Walters, Caroline E., Wang, Haowei, Atchison, Christina, Fronterre, Claudio, Diggle, Peter J., Ashby, Deborah, Donnelly, Christl A., Cooke, Graham, Barclay, Wendy, Ward, Helen, Darzi, Ara, Elliott, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158959/
https://www.ncbi.nlm.nih.gov/pubmed/33893241
http://dx.doi.org/10.1126/science.abf0874
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author Riley, Steven
Ainslie, Kylie E. C.
Eales, Oliver
Walters, Caroline E.
Wang, Haowei
Atchison, Christina
Fronterre, Claudio
Diggle, Peter J.
Ashby, Deborah
Donnelly, Christl A.
Cooke, Graham
Barclay, Wendy
Ward, Helen
Darzi, Ara
Elliott, Paul
author_facet Riley, Steven
Ainslie, Kylie E. C.
Eales, Oliver
Walters, Caroline E.
Wang, Haowei
Atchison, Christina
Fronterre, Claudio
Diggle, Peter J.
Ashby, Deborah
Donnelly, Christl A.
Cooke, Graham
Barclay, Wendy
Ward, Helen
Darzi, Ara
Elliott, Paul
author_sort Riley, Steven
collection PubMed
description Surveillance of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has mainly relied on case reporting, which is biased by health service performance, test availability, and test-seeking behaviors. We report a community-wide national representative surveillance program in England based on self-administered swab results from ~594,000 individuals tested for SARS-CoV-2, regardless of symptoms, between May and the beginning of September 2020. The epidemic declined between May and July 2020 but then increased gradually from mid-August, accelerating into early September 2020 at the start of the second wave. When compared with cases detected through routine surveillance, we report here a longer period of decline and a younger age distribution. Representative community sampling for SARS-CoV-2 can substantially improve situational awareness and feed into the public health response even at low prevalence.
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spelling pubmed-81589592021-05-28 Resurgence of SARS-CoV-2: Detection by community viral surveillance Riley, Steven Ainslie, Kylie E. C. Eales, Oliver Walters, Caroline E. Wang, Haowei Atchison, Christina Fronterre, Claudio Diggle, Peter J. Ashby, Deborah Donnelly, Christl A. Cooke, Graham Barclay, Wendy Ward, Helen Darzi, Ara Elliott, Paul Science Reports Surveillance of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has mainly relied on case reporting, which is biased by health service performance, test availability, and test-seeking behaviors. We report a community-wide national representative surveillance program in England based on self-administered swab results from ~594,000 individuals tested for SARS-CoV-2, regardless of symptoms, between May and the beginning of September 2020. The epidemic declined between May and July 2020 but then increased gradually from mid-August, accelerating into early September 2020 at the start of the second wave. When compared with cases detected through routine surveillance, we report here a longer period of decline and a younger age distribution. Representative community sampling for SARS-CoV-2 can substantially improve situational awareness and feed into the public health response even at low prevalence. American Association for the Advancement of Science 2021-05-28 2021-04-23 /pmc/articles/PMC8158959/ /pubmed/33893241 http://dx.doi.org/10.1126/science.abf0874 Text en Copyright © 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution license (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Reports
Riley, Steven
Ainslie, Kylie E. C.
Eales, Oliver
Walters, Caroline E.
Wang, Haowei
Atchison, Christina
Fronterre, Claudio
Diggle, Peter J.
Ashby, Deborah
Donnelly, Christl A.
Cooke, Graham
Barclay, Wendy
Ward, Helen
Darzi, Ara
Elliott, Paul
Resurgence of SARS-CoV-2: Detection by community viral surveillance
title Resurgence of SARS-CoV-2: Detection by community viral surveillance
title_full Resurgence of SARS-CoV-2: Detection by community viral surveillance
title_fullStr Resurgence of SARS-CoV-2: Detection by community viral surveillance
title_full_unstemmed Resurgence of SARS-CoV-2: Detection by community viral surveillance
title_short Resurgence of SARS-CoV-2: Detection by community viral surveillance
title_sort resurgence of sars-cov-2: detection by community viral surveillance
topic Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158959/
https://www.ncbi.nlm.nih.gov/pubmed/33893241
http://dx.doi.org/10.1126/science.abf0874
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